Mimura Hidefumi, Akita Sadanori, Fujino Akihiro, Jinnin Masatoshi, Ozaki Mine, Osuga Keigo, Nakaoka Hiroki, Morii Eiichi, Kuramochi Akira, Aoki Yoko, Arai Yasunori, Aramaki Noriko, Inoue Masanori, Iwashina Yuki, Iwanaka Tadashi, Ueno Shigeru, Umezawa Akihiro, Ozeki Michio, Ochi Junko, Kinoshita Yoshiaki, Kurita Masakazu, Seike Shien, Takakura Nobuyuki, Takahashi Masataka, Tachibana Takao, Chuman Kumiko, Nagata Shuji, Narushima Mitsunaga, Niimi Yasunari, Nosaka Shunsuke, Nozaki Taiki, Hashimoto Kazuki, Hayashi Ayato, Hirakawa Satoshi, Fujikawa Atsuko, Hori Yumiko, Matsuoka Kentaro, Mori Hideki, Yamamoto Yuki, Yuzuriha Shunsuke, Rikihisa Naoaki, Watanabe Shoji, Watanabe Shinichi, Kuroda Tatsuo, Sugawara Shunsuke, Ishikawa Kosuke, Sasaki Satoru
Department of Radiology, St Marianna University School of Medicine, Kawasaki, Japan.
Department of Plastic Surgery, Wound Repair and Regeneration, School of Medicine, Fukuoka University, Fukuoka, Japan.
Pediatr Int. 2020 Mar;62(3):257-304. doi: 10.1111/ped.14077. Epub 2020 Mar 22.
The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence-based medicine (EBM) techniques and aimed at improvement of the outcomes. Clinical questions (CQs) were decided based on the important clinical issues. For document retrieval, key words for literature searches were set for each CQ and literature published from 1980 to the end of September 2014 was searched in Pubmed, Cochrane Library, and Japana Centra Revuo Medicina (JCRM). The strengths of evidence and recommendations acquired by systematic reviews were determined following the Medical Information Network Distribution System (MINDS) technique. A total of 33 CQs were used to compile recommendations and the subjects included efficacy of resection, sclerotherapy/embolization, drug therapy, laser therapy, radiotherapy, and other conservative treatment, differences in appropriate treatment due to the location of lesions and among symptoms, appropriate timing of treatment and tests, and pathological diagnosis deciding the diagnosis. Thus, the Japanese Clinical Practice Guidelines for Vascular Anomalies 2017 have been prepared as the evidence-based guidelines for the management of vascular anomalies.
目标是通过组织血管瘤和血管畸形的有效且高效治疗、确认安全性以及使治疗系统化，运用循证医学（EBM）技术并旨在改善治疗效果，来制定实施当前最佳治疗的指南。临床问题（CQs）基于重要的临床问题确定。对于文献检索，为每个CQ设定文献检索关键词，并在PubMed、Cochrane图书馆和日本医学中央杂志（JCRM）中检索1980年至2014年9月底发表的文献。通过系统评价获得的证据强度和推荐意见按照医学信息网络分发系统（MINDS）技术确定。总共33个CQ用于编制推荐意见，主题包括切除、硬化治疗/栓塞、药物治疗、激光治疗、放射治疗以及其他保守治疗的疗效，因病变部位和症状不同而导致的合适治疗差异，治疗和检查的合适时机，以及决定诊断的病理诊断。因此，《2017年日本血管异常临床实践指南》已作为血管异常管理的循证指南编制完成。
