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[高度近视准分子激光原位角膜磨镶术后人工晶状体度数预测的陷阱——病例报告、实用建议及文献综述]

[Pitfalls of IOL power prediction after photorefractive keratectomy for high myopia -- case report, practical recommendations and literature review].

作者信息

Seitz Berthold, Langenbucher Achim, Haigis Wolfgang

机构信息

Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen.

出版信息

Klin Monbl Augenheilkd. 2002 Dec;219(12):840-50. doi: 10.1055/s-2002-36943.

DOI:10.1055/s-2002-36943
PMID:12548468
Abstract

BACKGROUND AND PURPOSE

Published experience with eyes after keratorefractive correction of myopia indicates that insertion of the average keratometric readings into standard IOL power predictive formulas will frequently result in substantial undercorrection and postoperative hyperopic refraction or anisometropia after cataract surgery depending on the amount of myopia corrected previously. The purpose of this paper is to discuss the accentuated differences of various approaches to minimize IOL power miscalculations by describing a case report of a patient with excessive myopia as well as a review of the literature.

PATIENT AND METHODS

A 50-year old lady presented for cataract surgery on her left eye after having PRK seven years ago elsewhere (refraction - 25.5 - 3.0/20 degrees, central keratometric power 43.0 diopters [D]). Central power before cataract extraction was measured to be 35.5 D (Zeiss Keratometer) and 36.5 D (TMS-1 topography analysis) and refraction was - 3.0 D (before onset of index myopia). Orbscan slit scanning topography analysis displayed an anterior surface power of 36.8 D and a posterior surface power of - 9.3 D. Total axial length was 31.93 mm (optical biometry using Zeiss IOL-Master). The contralateral eye after PRK suffering from a comparable excessive myopia had required an exchange of the IOL implant because of intolerable anisohyperopia of + 6.0 D after primary cataract extraction elsewhere.

RESULTS

Corrected corneal power values for the left eye were calculated as follows: (1) spherical equivalent (SEQ) change at spectacle plane 19.0 D, (2) SEQ change at corneal plane 26.2 D, (3) separate consideration of anterior and posterior curvature 27.5 D, (4) consideration of the IOL power misprediction on the fellow eye 29.5 D, (5) subtraction of 24 % of the SEQ change at the spectacle plane from the actually measured keratometry value 29.7 D, (6) clinical estimate from regression analysis performed earlier 30.5 D, (7) change of anterior surface power 34.5 D. Deciding for a presumably "real" corneal power of 28.0 D the Haigis formula was used to aim for - 2.0 D since the patient preferred to read uncorrected. Thus, a 21.0 D IOL was implanted uneventfully in the capsular bag. The stable refraction postoperatively was - 3.5 - 1.0/20 degrees and visual acuity increased to 20/30. Therefore, the "real" power of that cornea must have been around 30 D.

CONCLUSIONS

After corneal refractive surgery, various techniques to determine the current corneal power should be compared and the value around which results tend to cluster should be relied on to avoid hyperopia after cataract surgery with lens implantation. In those cases where keratometry and refraction before PRK/LASIK are available, the gold standard is still to subtract the change of the SEQ at the corneal plane from the preoperative central keratometric power, although in the present case report the subtraction of 24 % of the SEQ change at the spectacle plane from the measured corneal power value seemed to produce the best result. Pure subtraction of the SEQ change at the spectacle plane from the corneal power value before refractive surgery has to be avoided in eyes with excessive myopia. The most reliable corrected power value should be inserted in more than one modern third-generation formula (such as Haigis, Hoffer Q, Holladay 2, SRK/T) and the highest power IOL should be implanted. In all instances, the cataract surgeon has to make sure that the corrected K-reading is not wrongly re-converted within the IOL power calculation formula used.

摘要

背景与目的

已发表的关于近视角膜屈光矫正术后眼睛的经验表明,将平均角膜曲率读数代入标准人工晶状体(IOL)屈光力预测公式,常常会导致明显的矫正不足,以及白内障手术后出现远视性屈光不正或屈光参差,这取决于先前矫正的近视度数。本文旨在通过描述一例高度近视患者的病例报告以及文献综述,来讨论各种方法在尽量减少IOL屈光力计算错误方面的显著差异。

患者与方法

一位50岁女性,7年前在其他地方接受了准分子原位角膜磨镶术(PRK)后,前来为其左眼进行白内障手术(验光:-25.5 - 3.0/20度,中央角膜屈光力43.0屈光度[D])。白内障摘除术前测量的中央屈光力为35.5 D(蔡司角膜曲率计)和36.5 D(TMS-1地形图分析),验光为-3.0 D(近视指数出现之前)。Orbscan裂隙扫描地形图分析显示前表面屈光力为36.8 D,后表面屈光力为-9.3 D。眼轴总长度为31.93 mm(使用蔡司IOL-Master进行光学生物测量)。对侧眼在PRK后患有类似的高度近视,在其他地方初次白内障摘除术后因出现+6.0 D的无法耐受的屈光参差,需要更换IOL植入物。

结果

左眼矫正后的角膜屈光力值计算如下:(1)眼镜平面的等效球镜度(SEQ)变化为19.0 D,(2)角膜平面的SEQ变化为26.2 D,(3)分别考虑前后曲率为27.5 D,(4)考虑对侧眼的IOL屈光力预测错误为29.5 D,(5)从实际测量的角膜曲率值中减去眼镜平面SEQ变化的24%为29.7 D,(6)根据早期进行的回归分析的临床估计为30. D,(7)前表面屈光力变化为34.5 D。确定假定的“实际”角膜屈光力为28.0 D后,由于患者希望不矫正阅读,使用海吉斯公式目标为-2.0 D。因此,一个21.0 D的IOL顺利植入囊袋内。术后稳定的验光结果为-3.5 - 1.0/20度,视力提高到20/30。因此,该角膜的“实际”屈光力一定在30 D左右。

结论

角膜屈光手术后,应比较各种确定当前角膜屈光力的技术,并依靠结果趋于聚集的那个值,以避免白内障晶状体植入术后出现远视。在有PRK/LASIK术前角膜曲率和验光数据的情况下,金标准仍然是从术前中央角膜曲率值中减去角膜平面SEQ的变化,尽管在本病例报告中,从测量的角膜屈光力值中减去眼镜平面SEQ变化的24%似乎产生了最佳结果。对于高度近视的眼睛,必须避免直接从屈光手术前的角膜屈光力值中减去眼镜平面SEQ的变化。最可靠的矫正屈光力值应代入不止一个现代第三代公式(如海吉斯、霍弗Q、霍拉迪2、SRK/T),并应植入最高屈光力的IOL。在所有情况下,白内障手术医生必须确保在使用的IOL屈光力计算公式内,矫正后的角膜曲率读数不会被错误地重新转换。

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