Zhang H, Zhang X, Zheng R L, Gao Q X, Wei Z Q, Li W J, Chen W Q, Liang J P, Han G W, Huang T, Xie H M
Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000
Shi Yan Sheng Wu Xue Bao. 2000 Jun;33(2):97-100.
The testes of the B6C3F1 hybrid strain mice were irradiated with 0.05 Gy of 16O8+ ion as the pre-exposure dose (D1), and were then irradiated with 2 Gy of 16O8+ ion as challenging radiation dose (D2) at 4 h after per-exposure. Testicular morphology was observed by light microscope at 35th day after radiation. The results showed that irradiation of mouse testes with 2 Gy of 16O8+ ion significantly impaired, mainly reduction of tubule diameter and decrease or loss of germ cells in various developing stages, especially spermatogenic elements. Pre-exposure to a low-dose (0.05 Gy) of 16O8+ ion significantly alleviated above mentioned damage on testicular morphology induced by subsequent a high-dose (2 Gy) radiation.
