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因心力衰竭住院患者诊断和治疗资源的使用:入院病房类型的影响(INCARGAL研究)

[Use of diagnostic and therapeutic resources in patients hospitalized for heart failure: influence of admission ward type (INCARGAL Study)].

作者信息

García Castelo Alberto, Muñiz García Javier, Sesma Sánchez Pascual, Castro Beiras Alfonso

机构信息

Complejo Hospitalario Xeral-Calde, Lugo, Spain.

出版信息

Rev Esp Cardiol. 2003 Jan;56(1):49-56. doi: 10.1016/s0300-8932(03)76821-3.

Abstract

BACKGROUND

Heart failure (HF) is the most rapidly growing cardiac pathology in industrialized countries, and already the primary cause of hospital admissions of elderly people. Outside the field of clinical trials, there have not been many studies in Spain of the influence of the admission department on diagnostic and therapeutic management, whether this affects short-term and long-term prognosis, and the factors that determine the department the patient is admitted to.

OBJECTIVE

. To analyze whether management and prognosis of patients admitted with heart failure differ depending on the admission ward (cardiology versus internal medicine-geriatrics).

PATIENTS AND METHODS

Cross-sectional study of 951 patients (505 men and 446 women) consecutively hospitalized for HF in the cardiology (n = 363) and internal medicine-geriatrics (n = 588) wards of 12 hospitals of Galicia and recruited over a maximum period of 6 months. The main epidemiological and clinical variables were recorded at admission, and the complications, treatments, and clinical status were recorded at release.Results. HF patients had a mean age of 75.5 12 years (women 78.5 years and men 72.6 years). The average hospitalization time was 11 8 days and 50.8% were first admissions. Total hospital mortality was 6.8%. Fifty-nine percent (58.9%) of patients had arterial hypertension, 31.9% ischemic heart disease, 27.6% cardiac valve disease, 28.5% diabetes mellitus, and 32.5% chronic obstructive pulmonary disease (COPD). The patients admitted to cardiology ward were younger (72.5 13 vs 77.4 11 years; p < 0.005), more frequently men (51.9 vs 43.7%; p < 0.005), more often first hospitalizations (54.8 vs 48.4%; p < 0.005), and acute pulmonary edema was more common (22.8 vs 9.2%; p < 0.005). The odds ratio (and 95% CI) for therapeutic and diagnostic procedures in relation to admission ward (reference group internal medicine-geriatrics), adjusted for age, sex, systolic function, number of hospitalizations, and history of dementia, hypertension, COPD, AMI, valve disease and ischemic heart disease, are: echocardiogram, 3.49 (2.58-4.73); catheterization, 6.42 (3.29-12.55), admission to intensive care, 3.94 (2.15-7.25), revascularization, 2.15 (0.57-8.08), and beta-blocker treatment, 3.39 (1.93-5.97). No differences in hospital mortality (6.6% in cardiology vs 7% in internal medicine-geriatrics) or average hospitalization time were found between departments.

CONCLUSIONS

The admission ward was related with a clear difference in HF management, with better adherence to guidelines and more use of resources by cardiologists. This was unrelated with differences in hospital mortality so a longer follow-up of these patients is required to evaluate the impact of these therapeutic measures on the prognosis and evolution of HF, as well as the cost-benefit relation in an elderly patient population.

摘要

背景

心力衰竭(HF)是工业化国家中增长最为迅速的心脏疾病,并且已然是老年人住院的主要原因。在临床试验领域之外,西班牙针对收治科室对诊断和治疗管理的影响、这是否会影响短期和长期预后以及决定患者收治科室的因素开展的研究并不多。

目的

分析因心力衰竭入院的患者,其治疗管理和预后是否因收治病房(心内科与内科老年病科)的不同而存在差异。

患者与方法

对加利西亚地区12家医院心内科(n = 363)和内科老年病科(n = 588)连续收治的951例心力衰竭患者(505例男性和446例女性)进行横断面研究,招募时间最长为6个月。记录入院时的主要流行病学和临床变量,以及出院时的并发症、治疗情况和临床状态。结果:心力衰竭患者的平均年龄为75.5±12岁(女性78.5岁,男性72.6岁)。平均住院时间为11±8天,50.8%为首次入院。医院总死亡率为6.8%。59%(58.9%)的患者患有动脉高血压,31.9%患有缺血性心脏病,27.6%患有心脏瓣膜病,28.5%患有糖尿病,32.5%患有慢性阻塞性肺疾病(COPD)。入住心内科病房的患者更年轻(72.5±13岁 vs 77.4±11岁;p < 0.005),男性比例更高(51.9% vs 43.7%;p < 0.005),首次住院的比例更高(54.8% vs 48.4%;p < 0.005),急性肺水肿更为常见(22.8% vs 9.2%;p < 0.005)。针对收治病房(参照组为内科老年病科),在对年龄、性别、收缩功能、住院次数以及痴呆、高血压、COPD、急性心肌梗死、瓣膜病和缺血性心脏病病史进行校正后,治疗和诊断程序的优势比(及95%置信区间)如下:超声心动图检查为3.49(2.58 - 4.73);导管插入术为6.42(3.29 - 12.55),入住重症监护病房为3.94(2.15 - 7.25),血管重建术为2.15(0.57 - 8.08),β受体阻滞剂治疗为3.39(1.93 - 5.97)。各科室之间在医院死亡率(心内科为6.6%,内科老年病科为7%)或平均住院时间方面未发现差异。

结论

收治病房与心力衰竭的治疗管理存在明显差异相关,心内科医生对指南的遵循情况更好且资源使用更多。这与医院死亡率的差异无关,因此需要对这些患者进行更长时间的随访,以评估这些治疗措施对心力衰竭预后和病程的影响,以及老年患者群体中的成本效益关系。

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