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雌激素和孕激素不同组合对去卵巢兔卵子运输的影响

Egg transport in ovariectomized rabbits as affected by different combinations of oestrogen and progesterone.

作者信息

El-Banna A A, Sacher B

出版信息

J Endocrinol. 1976 Feb;68(02):331-40. doi: 10.1677/joe.0.0680331.

DOI:10.1677/joe.0.0680331
PMID:1255044
Abstract

A total of 1548 eggs was transferred to the oviducts of rabbits ovariectomized 45 days to 7 months earlier. The pattern of egg transport was disrupted, and the majority of eggs were in the vagina 60-72 h after transfer. To determine the role of the ovarian hormones on egg transport, the effects of various combinations of oestrogen and progesterone were studied. None of the hormonal treatments produced the normal transport pattern and large proportions of transferred eggs were retained in the oviducts. It is concluded that as long as progesterone is the dominant hormone, eggs move very slowly through the isthmus, and that a surge of oestrogen is required to modify the action of progesterone and to speed the movement of eggs to the uterus.

摘要

总共1548枚卵子被移植到45天至7个月前已切除卵巢的兔子的输卵管中。卵子运输模式被打乱,大多数卵子在移植后60 - 72小时位于阴道内。为了确定卵巢激素在卵子运输中的作用,研究了雌激素和孕酮不同组合的影响。没有一种激素处理能产生正常的运输模式,大量移植的卵子滞留在输卵管中。得出的结论是,只要孕酮是主导激素,卵子通过峡部的移动就非常缓慢,需要雌激素激增来改变孕酮的作用并加速卵子向子宫的移动。

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