重症肌无力、多发性肌炎和皮肌炎患者的血清免疫球蛋白水平。
Serum immunogloblin levels in myasthenia gravis, polymyositis, and dermatomyositis.
作者信息
Lisak R P, Zweiman B
出版信息
J Neurol Neurosurg Psychiatry. 1976 Jan;39(1):34-7. doi: 10.1136/jnnp.39.1.34.
Abstract
Analyses of serum immunoglobulin (Ig) levels were performed in patients with myasthenia gravis, polymyositis and dermatomyositis, and in normal subjects. The mean IgG levels were elevated in the disease groups and there was minimal depression of serum IgM levels in nonthymectomized myasthenic patients. There was no consistent pattern with regard to selective immunoglobulin class abnormalities, effect of thymectomy in serial studies, and no evidence of gross humoral immunological deficiency as manifested by consistent depression of serum IgA, IgG, or IgM in the disease groups.
摘要
对重症肌无力、多发性肌炎和皮肌炎患者以及正常受试者进行了血清免疫球蛋白（Ig）水平分析。疾病组的平均IgG水平升高，未进行胸腺切除术的重症肌无力患者血清IgM水平有轻微降低。在选择性免疫球蛋白类别异常、胸腺切除术在系列研究中的效果方面，没有一致的模式，并且疾病组中也没有证据表明存在血清IgA、IgG或IgM持续降低所表现出的明显体液免疫缺陷。
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