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[术中知晓]

[Intraoperative awareness].

作者信息

Schneider G

机构信息

Klinik für Anaesthesiologie der Technischen Universität München, Klinikum rechts der Isar, München.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2003 Feb;38(2):75-84. doi: 10.1055/s-2003-36993.

Abstract

The first cases of general anesthesia were already cases with awareness. Until today, case reports of patients with awareness are published. These published cases are likely to be the top of the iceberg, as most patients with postoperative recall do not inform their anesthesiologist. Incidence of awareness with recall is between 0.1 and 0.2 %. In a large multicenter-study, incidence of recall was 0.1 % without, and 0.18 % with the use of muscle relaxants. The risk is increased with decreased doses of anesthetics, e.g. in patients with hemodynamic instability (trauma cases), patients undergoing cesarean section or cardiac surgery. Intraoperative awareness does not necessarily cause explicit (conscious) memory. Even in the absence of explicit memory, implicit (unconscious) memory can still have consequences for the patient. In the worst case, it can cause post-traumatic stress disorder. There is doubt whether patients may profit from positive suggestions given during intraoperative awareness. Recommendations to administer benzodiazepines to prevent explicit memory must be reconsidered. Complete neuromuscular block should be avoided whenever possible. If a patient is thought to be aware, he should be contacted, his situation should be explained and affirming comments should be given until consciousness is lost again. Postoperative visit should include questions about awareness and recall. The anesthetist should not disbelieve reported recall. Explanation of what had happened and referral to an experienced psychologist must be offered. Thus, the incidence of severe sequelae should decrease.

摘要

首例全身麻醉病例就已存在术中知晓情况。直至今日,仍有术中知晓患者的病例报告发表。这些已发表的病例可能只是冰山一角,因为大多数术后发生回忆的患者并未告知其麻醉医生。术中知晓伴回忆的发生率在0.1%至0.2%之间。在一项大型多中心研究中,未使用肌肉松弛剂时回忆发生率为0.1%,使用时为0.18%。麻醉药剂量减少时风险会增加,例如在血流动力学不稳定的患者(创伤病例)、接受剖宫产或心脏手术的患者中。术中知晓不一定会导致明确(有意识)的记忆。即使没有明确记忆,隐性(无意识)记忆仍可能对患者产生影响。在最糟糕的情况下,它会导致创伤后应激障碍。患者是否能从术中知晓期间给予的积极暗示中获益尚存在疑问。关于使用苯二氮䓬类药物预防明确记忆的建议必须重新考虑。应尽可能避免完全性神经肌肉阻滞。如果认为患者处于知晓状态,应与其沟通,向其解释情况并给予肯定性评论,直至其再次失去意识。术后访视应包括询问患者是否有术中知晓和回忆。麻醉医生不应怀疑患者报告的回忆情况。必须对所发生的事情进行解释,并转介给经验丰富的心理学家。这样,严重后遗症的发生率应会降低。

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