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玻利维亚圣克鲁斯一个普通外科病房手术部位感染的发生率及国家医院感染监测系统风险指数的有效性

Incidence of surgical-site infections and the validity of the National Nosocomial Infections Surveillance System risk index in a general surgical ward in Santa Cruz, Bolivia.

作者信息

Soleto Lorena, Pirard Marianne, Boelaert Marleen, Peredo Remberto, Vargas Reinerio, Gianella Alberto, Van der Stuyft Patrick

机构信息

Centro Nacional de Enfermedades Tropicales (CENETROP), Santa Cruz, Bolivia.

出版信息

Infect Control Hosp Epidemiol. 2003 Jan;24(1):26-30. doi: 10.1086/502111.

Abstract

OBJECTIVES

To estimate the frequency of and risk factors for surgical-site infections (SSIs) in Bolivia, and to study the performance of the National Nosocomial Infections Surveillance (NNIS) System risk index in a developing country.

DESIGN

A prospective study with patient follow-up until the 30th postoperative day.

SETTING

A general surgical ward of a public hospital in Santa Cruz, Bolivia.

PATIENTS

Patients admitted to the ward between July 1998 and June 1999 on whom surgical procedures were performed.

RESULTS

Follow-up was complete for 91.5% of 376 surgical procedures. The overall SSI rate was 12%. Thirty-four (75.6%) of the 45 SSIs were culture positive. A logistic regression model retained an American Society of Anesthesiologists score of more than 1 (odds ratio [OR], 1.87), a not-clean wound class (OR, 2.28), a procedure duration of more than 1 hour (OR, 1.81), and drain (OR, 1.98) as independent risk factors for SSI. There was no significant association between the NNIS System risk index and SSI rates. However, a "local" risk index constructed with the above cutoff points showed a linear trend with SSI (P < .001) and a relative risk of 3.18 for risk class 3 versus a class of less than 3.

CONCLUSIONS

SSIs cause considerable morbidity in Santa Cruz. Appropriate nosocomial infection surveillance and control should be introduced. The NNIS System risk index did not discriminate between patients at low and high risk for SSI in this hospital setting, but a risk score based on local cutoff points performed substantially better.

摘要

目的

评估玻利维亚手术部位感染(SSI)的发生率及危险因素,并研究国家医院感染监测(NNIS)系统风险指数在发展中国家的表现。

设计

一项前瞻性研究,对患者进行术后30天的随访。

地点

玻利维亚圣克鲁斯一家公立医院的普通外科病房。

患者

1998年7月至1999年6月间入住该病房并接受手术的患者。

结果

376例手术中有91.5%的患者完成了随访。总体SSI发生率为12%。45例SSI中有34例(75.6%)培养结果呈阳性。逻辑回归模型确定,美国麻醉医师协会评分大于1(比值比[OR],1.87)、伤口清洁度为非清洁(OR,2.28)、手术持续时间超过1小时(OR,1.81)以及放置引流管(OR,1.98)为SSI的独立危险因素。NNIS系统风险指数与SSI发生率之间无显著关联。然而,根据上述临界点构建的“本地”风险指数与SSI呈线性趋势(P <.001),风险等级3相对于低于3级的相对风险为3.18。

结论

SSI在圣克鲁斯导致相当高的发病率。应引入适当的医院感染监测和控制措施。在该医院环境中,NNIS系统风险指数无法区分SSI低风险和高风险患者,但基于本地临界点的风险评分表现要好得多。

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