波动泵全人工心脏的第三种型号。
Third model of the undulation pump total artificial heart.
作者信息
Abe Yusuke, Chinzei Tsuneo, Isoyama Takashi, Ono Toshiya, Mochizuki Shuichi, Saito Itsuro, Iwasaki Kiyotaka, Ishimaru Mitsuhiko, Baba Atsushi, Kouno Akimasa, Ozeki Toshinaga, Tohyama Takahiro, Imachi Kou
机构信息
Department of Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan 113-0033.
出版信息
ASAIO J. 2003 Jan-Feb;49(1):123-7. doi: 10.1097/00002480-200301000-00020.
The undulation pump is a small, continuous flow displacement type blood pump, and the undulation pump total artificial heart (UPTAH) is a unique, implantable total artificial heart based on this pump. To improve the durability of the UPTAH for investigating long-term pathophysiology with UPTAH, a third model (UPTAH3) has been developed. UPTAH3 was designed to separate the left and right undulation shafts and to be more durable. The undulation pumps were also redesigned. UPTAH3 was implemented with a diameter of 76 mm, width of 78 or 79 mm, total volume of 292 ml, and weight of 620 g. The priming volumes of the left and right pumps are 26 and 21 ml, respectively. The atrial cuffs and outflow cannulae were also redesigned for UPTAH3. The maximum output against an arterial pressure load of 100 mm Hg is about 11 L/min. The maximum pump efficiency is about 15% in the left pump and 18% in the right pump, giving a maximum total efficiency for both of about 11%. To date, UPTAH3 has been tested in 17 goats, and the longest survival period was 46 days. This third model will be useful for investigating pathophysiology with UPTAH.
波动泵是一种小型的连续流置换式血泵，而波动泵全人工心脏（UPTAH）是基于该泵的一种独特的可植入式全人工心脏。为了提高UPTAH的耐久性以用于研究UPTAH的长期病理生理学，已开发出第三种型号（UPTAH3）。UPTAH3的设计是将左右波动轴分开，并且更耐用。波动泵也进行了重新设计。UPTAH3的直径为76毫米，宽度为78或79毫米，总体积为292毫升，重量为620克。左右泵的预充量分别为26毫升和21毫升。心房袖带和流出插管也针对UPTAH3进行了重新设计。在100毫米汞柱的动脉压力负荷下的最大输出约为11升/分钟。左泵的最大泵效率约为15%，右泵为18%，两者的最大总效率约为11%。迄今为止，UPTAH3已在17只山羊身上进行了测试，最长存活期为46天。这种第三种型号将有助于用UPTAH研究病理生理学。
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