波动泵全人工心脏控制系统的进展

Progress in the control system of the undulation pump total artificial heart.

作者信息

Saito Itsuro, Chinzei Tsuneo, Abe Yusuke, Ishimaru Mitsuhiko, Mochizuki Shuichi, Ono Toshiya, Isoyama Takashi, Iwasaki Kiyotaka, Kouno Akimasa, Baba Atsushi, Ozeki Toshinaga, Takiura Koki, Tohyama Takahiro, Nakagawa Hidemoto, Imachi Kou

机构信息

Research Center for Advanced Science and Technology, The University of Tokyo, Japan.

出版信息

Artif Organs. 2003 Jan;27(1):27-33. doi: 10.1046/j.1525-1594.2003.07174.x.

DOI:10.1046/j.1525-1594.2003.07174.x

PMID:12534710

Abstract

The undulation pump total artificial heart (UPTAH) is a small implantable total artificial heart. As the UPTAH generates outflow and inflow at the same time, control of the UPTAH is very difficult. Therefore suitable control methods specifically for the UPTAH should be established. Various motor control, left-right flow balance control, and physiological control methods were examined and tried for the UPTAH control in this study. The control system is divided into seven categories. It has a hierarchical structure and all control modes work at the same time. The UPTAH with the newly developed control method has been implanted into the chest cavities of 48 goats. Until now, six goats survived for more than one month, including 63 days in the longest case. The good condition of the UPTAH implanted animal could be maintained with the newly developed control scheme, consisting of the 1/R control and several other additional controls.

摘要

波动泵全人工心脏（UPTAH）是一种小型可植入式全人工心脏。由于UPTAH同时产生流出和流入，对其进行控制非常困难。因此，应建立专门适用于UPTAH的控制方法。本研究对各种电机控制、左右流量平衡控制和生理控制方法进行了研究并尝试用于UPTAH控制。控制系统分为七类。它具有分层结构，所有控制模式同时工作。采用新开发控制方法的UPTAH已植入48只山羊的胸腔。到目前为止，有6只山羊存活超过1个月，最长的一例存活了63天。采用由1/R控制和其他几种附加控制组成的新开发控制方案，可以维持植入UPTAH动物的良好状态。