Alexopoulos Dimitrios, Toulgaridis Theodoros, Davlouros Periklis, Christodoulou John, Stathopoulos Christos, Hahalis George
Division of Cardiology, Department of Medicine, University of Patras Medical School, 26500 Rio, Patras, Greece.
Int J Cardiol. 2003 Feb;87(2-3):159-66. doi: 10.1016/s0167-5273(02)00209-7.
Coronary artery calcium, detected non-invasively, correlates well with angiographically documented coronary artery disease (CAD). This study was conducted to evaluate the diagnostic efficacy of coronary artery calcium detected by digital cinefluoroscopy for CAD and assess the effects of age and sex on it.
In 242 patients who underwent coronary angiography, coronary calcium status was determined and related to angiographic findings.
Calcium detection had a sensitivity 85%, specificity 52%, positive predictive value 92%, negative predictive value 33% and diagnostic accuracy 81% for significant CAD. There was a better positive predictive value in men (95% vs. 80%) and negative predictive value in women (65% vs. 16%), while a higher sensitivity and diagnostic accuracy was found in older than in younger (90% and 86% vs. 78% and 74%). The sensitivity of the method increased with the number of the diseased vessels.
Coronary calcium can be quite accurately detected by digital cinefluoroscopy. This, however, should be made in the context of sex and age.
通过无创检测的冠状动脉钙化与血管造影记录的冠状动脉疾病（CAD）密切相关。本研究旨在评估数字电影荧光透视法检测冠状动脉钙化对CAD的诊断效能，并评估年龄和性别对其的影响。
对242例行冠状动脉造影的患者进行冠状动脉钙化状况测定，并将其与血管造影结果相关联。
对于显著CAD，钙化检测的敏感性为85%，特异性为52%，阳性预测值为92%，阴性预测值为33%，诊断准确性为81%。男性的阳性预测值更高（95%对80%），女性的阴性预测值更高（65%对16%），而年龄较大者的敏感性和诊断准确性高于年龄较小者（90%和86%对78%和74%）。该方法的敏感性随病变血管数量增加而提高。
数字电影荧光透视法能够相当准确地检测冠状动脉钙化。然而，这应结合性别和年龄来进行判断。
