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[食物诱发的嗜酸性粒细胞性直肠结肠炎。1例报告]

[Eosinophilic proctocolitis induced by foods. Report of a case].

作者信息

Cordero Miranda Miguel Angel, Blandón Vijil Virginia, Reyes Ruiz Norma Isabel, Avila Castañón Lourdes, del Río Navarro Blanca Estela, García Aranda José Alberto, Blanco Rodríguez Gerardo, Sienra Monge Juan José Luis

机构信息

Departamento de alergia e inmunología clinica, Hospital Infantil de México Federico Gómez.

出版信息

Rev Alerg Mex. 2002 Nov-Dec;49(6):196-9.

Abstract

The food-induced eosinophilic proctocolitis is a major cause of blood-tinged stools and appears in the first two months of life. The infant is generally described as well, but the clinical features and laboratory results are often nonspecific. We present an early infant with fresh blood stools at 50 days. The colonoscopy and biopsy of the rectum and lower sigmoid revealed lymphoid nodular hyperplasia of the submucose and eosinophil infiltration (40 to 50 per high power field) of the lamina propria and intraepithelial. Elimination of the offending protein from the diet, through the use of an extensively hydrolyzed casein-based formula and soy, lead to clinical resolution of bleeding at 48 hours. We made a review of the case.

摘要

食物诱导的嗜酸性粒细胞性直肠结肠炎是便血的主要原因,出现在出生后的头两个月。婴儿一般情况良好,但临床特征和实验室检查结果往往不具有特异性。我们报告一例50日龄出现新鲜便血的早期婴儿。结肠镜检查及直肠和乙状结肠下段活检显示黏膜下淋巴结节增生,固有层和上皮内有嗜酸性粒细胞浸润(每高倍视野40至50个)。通过使用深度水解酪蛋白配方奶粉和大豆从饮食中去除致敏蛋白后,48小时内出血症状临床缓解。我们对该病例进行了回顾。

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