Ribeiro J, Mathieson S I
Br J Vener Dis. 1975 Aug;51(4):272-3. doi: 10.1136/sti.51.4.272.
Of 104 male and nine female patients with uncomplicated acute gonorrhoea who were treated with spectinomycin (males 2 g., females 4 g.), two patients (one male and one female) were considered to be treatment failures. No conclusions can be drawn from the small numbers of female patients investigated. Of the 104 male patients, 93 were followed for 2 weeks or more, giving a failure rate of 1-1 per cent. The drug was well tolerated. Sensitivity tests were carried out on 44 strains of N. gonorrhoeae; 42 strains were sensitive to 2-5 mug./ml. spectinomycin and all strains were sensitive to 5 mug./ml.
对104例男性和9例女性单纯性急性淋病患者使用壮观霉素进行治疗（男性2克，女性4克），有2例患者（1例男性和1例女性）被视为治疗失败。由于所研究的女性患者数量较少，无法得出结论。在104例男性患者中，93例随访了2周或更长时间，失败率为1.1%。该药物耐受性良好。对44株淋病奈瑟菌进行了敏感性试验；42株对2 - 5微克/毫升壮观霉素敏感，所有菌株对5微克/毫升敏感。
