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Treatment of uncomplicated gonorrhoea with spectinomycin hydrochloride (Trobicin).

作者信息

Porter I A, Rutherford H W

出版信息

Br J Vener Dis. 1977 Apr;53(2):115-7. doi: 10.1136/sti.53.2.115.

Abstract

110 patients with uncomplicated gonococcal urethritis were treated with 2 g spectinomycin (Trobicin) intramuscularly. Seventy-five patients were available for follow-up and there was only one treatment failure, giving a cure rate of 98-6%. Of the 99 gonococcal isolates, 59 were sensitive to 5 microng/ml of spectinomycin or less and 40 were sensitive to 10 microng/ml. In a small sample of patients 2 g spectinomycin intramuscularly produced a serum concentration averaging 100 microng/ml after one hour.

摘要

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本文引用的文献

1
Treatment of gonorrhoea with actinospectacin.
Br J Vener Dis. 1962 Jun;38(2):60-3. doi: 10.1136/sti.38.2.60.
4
Spectinomycin: minimum inhibitory concentrations for Neisseria gonorrhoeae.
Br J Vener Dis. 1974 Aug;50(4):289-90. doi: 10.1136/sti.50.4.289.
5
Spectinomycin in the treatment of gonorrhoea in males.
Br J Vener Dis. 1974 Aug;50(4):294-7. doi: 10.1136/sti.50.4.294.
6
Spectinomycin hydrochloride in the treatment of uncomplicated gonorrhoea in males and females.
Br J Vener Dis. 1974 Aug;50(4):291-3. doi: 10.1136/sti.50.4.291.
7
Treatment of gonorrhoea with spectinomycin hydrochloride.
Br J Vener Dis. 1973 Feb;49(1):60-1. doi: 10.1136/sti.49.1.60.

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