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菊苣毛状根培养物中的倍半萜内酯

Sesquiterpene lactones in a hairy root culture of Cichorium intybus.

作者信息

Malarz Janusz, Stojakowska Anna, Kisiel Wanda

机构信息

Department of Phytochemistry, Institute of Pharmacology, Polish Academy of Sciences, Smetna Street 12, 31-343 Kraków, Poland.

出版信息

Z Naturforsch C J Biosci. 2002 Nov-Dec;57(11-12):994-7. doi: 10.1515/znc-2002-11-1207.

Abstract

A transformed root culture of Cichorium intybus L. (Asteraceae) was found to produce sesquiterpene lactones of guaiane and germacrane type. Lactucopicrin, 8-desoxylactucin and three sesquiterpene lactone glycosides: crepidiaside B, sonchuside A and ixerisoside D were isolated from the roots. The yield of 8-desoxylactucin reached 0.03 g l(-1) at the early stationary phase of the culture.

摘要

已发现菊苣(菊科)的转化根培养物能产生愈创木烷型和吉马烷型倍半萜内酯。从根部分离出了莴苣苦素、8-去氧莴苣素以及三种倍半萜内酯糖苷:crepidiaside B、苦苣菜苷A和苦荬菜苷D。在培养的早期稳定期,8-去氧莴苣素的产量达到0.03 g l(-1)。

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