Yuan Shan, Vaughan Matthew, Agoff S Nicholas
Department of Pathology, Harborview Medical Center/University of Washington Medical Center, Seattle, WA 98195, USA.
Arch Pathol Lab Med. 2003 Jan;127(1):e1-3. doi: 10.5858/2003-127-e1-LSSFWM.
Occasionally, heterotopic splenic tissue can occur in the renal fossa secondary to splenosis following splenic trauma or splenectomy. More rarely, it can represent a developmental anomaly secondary to the fusion of splenic and renal tissues. Splenorenal fusion can present as a renal mass, mimicking primary or secondary renal neoplasms on imaging studies, and patients can also present with symptoms of hypersplenism (anemia). We report a case of splenorenal fusion in a 51-year-old woman who initially presented with lithium toxicity, anemia, thrombocytosis, and a large renal mass that mimicked a primary renal neoplasm. The possible embryologic origin of splenorenal fusion, effects of lithium toxicity, and utility of various imaging modalities are discussed. The literature on renal heterotopic splenic tissue is also briefly reviewed.
偶尔，脾脏外伤或脾切除术后因脾组织种植，异位脾组织可出现在肾窝。更罕见的是，它可能是脾脏和肾脏组织融合继发的发育异常。脾肾融合可表现为肾脏肿块，在影像学检查中酷似原发性或继发性肾肿瘤，患者还可能出现脾功能亢进症状（贫血）。我们报告一例51岁女性的脾肾融合病例，该患者最初表现为锂中毒、贫血、血小板增多症以及一个酷似原发性肾肿瘤的巨大肾脏肿块。文中讨论了脾肾融合可能的胚胎学起源、锂中毒的影响以及各种成像方式的作用。还简要回顾了关于肾异位脾组织的文献。
