Nam Jong H, Murthy Sreekant
Division of Gastroenterology and Hepatology, Drexel University College of Medicine, 245 N 15th Street, Philadelphia, PA 19102, USA.
Expert Opin Pharmacother. 2003 Feb;4(2):235-41. doi: 10.1517/14656566.4.2.235.
Acute pancreatitis is a life-threatening inflammatory disorder of the pancreas. Currently, there is no effective pharmacological therapy available for this disorder. The management strategies remain supportive. Given the remarkable morbidity and mortality associated with acute pancreatitis, there is clearly a desperate need for effective novel therapies. This paper presents a review on the epidemiology, aetiology, pathogenesis and management of acute pancreatitis and highlights the need for the development of novel and more specific therapies to battle this disorder.
急性胰腺炎是一种危及生命的胰腺炎症性疾病。目前,针对这种疾病尚无有效的药物治疗方法。治疗策略仍以支持治疗为主。鉴于急性胰腺炎相关的高发病率和死亡率,显然迫切需要有效的新型治疗方法。本文对急性胰腺炎的流行病学、病因、发病机制及治疗进行了综述,并强调了开发新型、更具特异性治疗方法以对抗这种疾病的必要性。