毒物兴奋效应与毒理学风险评估 - Suppr

Hormesis and toxicological risk assessment.

作者信息

Rodricks Joseph V

机构信息

ENVIRON International Corporation, Life Sciences, 4350 North Fairfax Drive, Suite 300, Arlington, Virginia 22203, USA.

出版信息

Toxicol Sci. 2003 Feb;71(2):134-6. doi: 10.1093/toxsci/71.2.134.

DOI:10.1093/toxsci/71.2.134

PMID:12563098

Abstract

摘要

相似文献

Hormesis and toxicological risk assessment.毒物兴奋效应与毒理学风险评估

Toxicol Sci. 2003 Feb;71(2):134-6. doi: 10.1093/toxsci/71.2.134.

Should hormesis be the default model in risk assessment?

Hum Exp Toxicol. 2005 May;24(5):243. doi: 10.1191/0960327105ht518ed.

Paradigm lost, paradigm found: the re-emergence of hormesis as a fundamental dose response model in the toxicological sciences.范式迷失，范式重现：毒物兴奋效应作为毒理学基础剂量反应模型的再度兴起。

Environ Pollut. 2005 Dec;138(3):379-411. doi: 10.1016/j.envpol.2004.10.001.

The implications of hormesis to ecotoxicology and ecological risk assessment.毒物兴奋效应在生态毒理学及生态风险评估中的意义。

Hum Exp Toxicol. 2001 Oct;20(10):499-505. doi: 10.1191/096032701718120337.

Commentary: hormesis and ecological risk assessment.

Hum Exp Toxicol. 2001 Oct;20(10):525-6; discussion 529-31. doi: 10.1191/096032701718120391.

The hormetic dose-response model is more common than the threshold model in toxicology.在毒理学中， hormetic剂量反应模型比阈值模型更为常见。

Toxicol Sci. 2003 Feb;71(2):246-50. doi: 10.1093/toxsci/71.2.246.

Hormesis--does it have relevance at the population, community or ecosystem levels of organization?

Hum Exp Toxicol. 2001 Oct;20(10):517-20; discussion 529-31. doi: 10.1191/096032701718120373.

[Toxicological basis for evaluating health risk].评估健康风险的毒理学依据

Med Pr. 1992;43(3):173-81.

How much is enough to accept hormesis as the default? or 'At what point, if ever, could/should hormesis be employed as the principal dose-response default assumption in risk assessment?'.

Hum Exp Toxicol. 2005 May;24(5):245-7. doi: 10.1191/0960327105ht519oa.

Hormesis: the dose-response revolution.毒物兴奋效应：剂量反应的变革

Annu Rev Pharmacol Toxicol. 2003;43:175-97. doi: 10.1146/annurev.pharmtox.43.100901.140223. Epub 2002 Jan 10.

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A web-based tool for designing experimental studies to detect hormesis and estimate the threshold dose.一种基于网络的工具，用于设计实验研究以检测 hormesis 并估计阈剂量。

Stat Pap (Berl). 2018 Dec;59(4):1307-1324. doi: 10.1007/s00362-018-1038-5. Epub 2018 Sep 5.

Lanthanum regulates the reactive oxygen species in the roots of rice seedlings.镧调控水稻幼苗根系中的活性氧。

Sci Rep. 2016 Aug 22;6:31860. doi: 10.1038/srep31860.

Optimal experimental design strategies for detecting hormesis.最优实验设计策略在检测毒物兴奋效应中的应用。

Risk Anal. 2011 Dec;31(12):1949-60. doi: 10.1111/j.1539-6924.2011.01625.x. Epub 2011 May 5.

The maturing of hormesis as a credible dose-response model.毒物兴奋效应作为一种可信剂量反应模型的成熟过程。

Nonlinearity Biol Toxicol Med. 2003 Jul;1(3):319-43. doi: 10.1080/15401420390249934.

An ethics of expertise based on informed consent.

Sci Eng Ethics. 2006 Oct;12(4):637-61. doi: 10.1007/s11948-006-0062-3.

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Hormesis and toxicological risk assessment.

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