Wang Z, Lou W, Zhang E, Zhang X, Xue C
Department of Parasitology, Shanghai Second Medical University, Shanghai 200025.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1999;17(4):203-4.
To investigate the feasibility of detecting anti-Schistosoma japonicum antibodies in saliva.
Saliva and serum samples of 5 infected, 7 reinfected and 8 treated rabbits were collected at different times periods. The CAb in saliva and serum was detected by using ELISA.
The sensitivity of ELISA was 94.7% for saliva and 100% for serum. The specificity of ELISA was 100% for both saliva and serum.
Saliva can be used to detect circulating antibodies for the diagnosis of schistosomiasis japonica.
探讨检测唾液中抗日本血吸虫抗体的可行性。
收集5只感染兔、7只再感染兔和8只治疗后兔在不同时间段的唾液和血清样本。采用酶联免疫吸附测定法（ELISA）检测唾液和血清中的循环抗体（CAb）。
ELISA检测唾液的敏感性为94.7%，检测血清的敏感性为100%。ELISA检测唾液和血清的特异性均为100%。
唾液可用于检测循环抗体以诊断日本血吸虫病。
