[日本血吸虫感染兔唾液中循环抗体检测的可行性研究]
[Studies on the feasibility of detecting circulating antibodies in saliva of Schistosoma japonicum infected rabbits].
作者信息
Wang Z, Lou W, Zhang E, Zhang X, Xue C
机构信息
Department of Parasitology, Shanghai Second Medical University, Shanghai 200025.
出版信息
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1999;17(4):203-4.
AIM
To investigate the feasibility of detecting anti-Schistosoma japonicum antibodies in saliva.
METHODS
Saliva and serum samples of 5 infected, 7 reinfected and 8 treated rabbits were collected at different times periods. The CAb in saliva and serum was detected by using ELISA.
RESULTS
The sensitivity of ELISA was 94.7% for saliva and 100% for serum. The specificity of ELISA was 100% for both saliva and serum.
CONCLUSION
Saliva can be used to detect circulating antibodies for the diagnosis of schistosomiasis japonica.
目的
探讨检测唾液中抗日本血吸虫抗体的可行性。
方法
收集5只感染兔、7只再感染兔和8只治疗后兔在不同时间段的唾液和血清样本。采用酶联免疫吸附测定法（ELISA）检测唾液和血清中的循环抗体（CAb）。
结果
ELISA检测唾液的敏感性为94.7%，检测血清的敏感性为100%。ELISA检测唾液和血清的特异性均为100%。
结论
唾液可用于检测循环抗体以诊断日本血吸虫病。
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