Li D, Jia T L, Qin R S
Department of Plastic Surgery, Third Hospital of Peking University, Beijing, P. R. China 100083.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2001 Jan;15(1):42-5.
To investigate the mechanism of electrothrombosis by copper needle, in order to supply the referential data for clinical treatment of vessel deformity.
The mechanism and condition of thrombus formation by copper needle were studied in vivo and in vitro using electrophysics, atom absorption spectrophtometry, histological, and histochemical methods.
Great deal of copper ion was dissociated, and agglutination of red blood cells(RBC) in blood could be observed in vitro after the current applied by copper needles. Formation of stable thrombus was related to voltage and time of application of electric current.
Dissociation of copper ion and agglutination of RBC are the basic principle of electrothrombosis with copper needle. A 4V direct current and 17.5 minutes are the safe and effective conditions for thrombus formation in the blood vessels.
探讨铜针电凝形成血栓的机制，为临床治疗血管畸形提供参考依据。
采用电物理学、原子吸收光谱法、组织学及组织化学方法，在体内和体外研究铜针形成血栓的机制及条件。
铜针通电后，体外血液中大量铜离子解离，可见红细胞凝集。稳定血栓的形成与电压及通电时间有关。
铜离子解离和红细胞凝集是铜针电凝形成血栓的基本原理。4V直流电及17.5分钟是血管内血栓形成的安全有效条件。
