Lu Y Y, Shen P, Ding W
Department of Otorhinolaryngology, First Affiliated Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310003.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2000 Dec;14(12):538-9.
To study the relationship between the microvascular density(MVD) and the prognosis in laryngeal cancer.
Microvessel quantitation in 31 cases of laryngeal cancer was done with factor VIII-related antibody and SABC method.
The quantitation of microvessels in laryngeal cancer were negative of histologic grade and type, but were significantly different (P < 0.05) between metastasis (10.23 +/- 0.78) and without metastasis(6.38 +/- 0.33) two years after operation.
The angiogenesis of laryngeal cancer is correlated with the lymph node metastasis and prognosis.