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联合木糖-乳糖耐量试验在疑似吸收不良儿童中的应用(作者译)

[The application of a combined Xylose-lactose tolerance-test in children with suspected malabsorption (author's transl)].

作者信息

Brügmann G, Niessen K H, Schmidt K, Höntzsch D

出版信息

Monatsschr Kinderheilkd (1902). 1976 Feb;124(2):54-8.

PMID:1256451
Abstract

A combined xylose-lactose tolerance-test and a duodenal biopsy were performed in 68 children with suspected malabsorption-syndrome. The purpose of the present work was to assess the diagnostic value of xylose concentrations in blood at different times and to determine the additional discriminatory value to glucose levels. The contribution of the glucose rise to a calculated discriminant function is statistically significant but practically negligible and therefore does not justify its determination. A small-bowel biopsy is recommended if the concentration of xylose after 60 min is less than 26 mg/100 ml or the increment of xylose concentration above fasting level is 18 mg/100 ml or less.

摘要

对68名疑似吸收不良综合征的儿童进行了木糖-乳糖联合耐受性测试和十二指肠活检。本研究的目的是评估不同时间血液中木糖浓度的诊断价值,并确定其相对于葡萄糖水平的额外鉴别价值。葡萄糖升高对计算出的判别函数的贡献在统计学上具有显著意义,但在实际中可忽略不计,因此没有理由测定它。如果60分钟后木糖浓度低于26mg/100ml,或木糖浓度高于空腹水平的增加值为18mg/100ml或更低,则建议进行小肠活检。

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