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血液木糖试验在吸收不良综合征患儿中的价值(作者译)

[The value of the blood xylose test in children with the malabsorption syndrome (author's transl)].

作者信息

Sommer R, Ploier R, Tulzer W

出版信息

Wien Klin Wochenschr. 1977 Mar 4;89(5):157-60.

PMID:842034
Abstract

Blood xylose levels were studied 30, 60 and 90 minutes after oral administration of D-xylose in 121 patients aged 2 months to 12 years with symptoms of malabsorption. The results show that the 60-minute test aline is sufficiently accurate and the dose of 15g xylose/m2 surface area seems perferable to a uniform dosage of 5g xylose. Reference values of blood xylose were determined in children with normal intestinal mucosa and prove a significant difference between babies and elder children. Comparison between the results of the xylose test in normal children and in different conditions of intestinal mucosa showed that the one-hour blood xylose test is of little value in the selection of cases requiring primary diagnostic intestinal biopsy in children with malabsorption. This test, however, might be valuable in the control of patients with diagnosed coeliac disease and as a screening test for other members of those families.

摘要

对121名年龄在2个月至12岁、有吸收不良症状的患者口服D-木糖后30、60和90分钟的血木糖水平进行了研究。结果表明,60分钟的检测线足够准确,每平方米体表面积15克木糖的剂量似乎比统一的5克木糖剂量更可取。在肠黏膜正常的儿童中测定了血木糖的参考值,结果表明婴儿和大龄儿童之间存在显著差异。对正常儿童和不同肠黏膜状况下木糖检测结果的比较表明,对于吸收不良的儿童,1小时血木糖检测在选择需要进行初步诊断性肠道活检的病例时价值不大。然而,该检测对于已确诊乳糜泻的患者的病情监测以及作为这些家庭其他成员的筛查检测可能是有价值的。

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