Meuleman E J H, Mulders P F A
Department of Urology, University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.
Eur Urol. 2003 Feb;43(2):95-101; discussion 101-2. doi: 10.1016/s0302-2838(02)00546-8.
Although the high rate of erectile dysfunction (ED) following prostatectomy is well recognised, the aetiology and pathophysiology have not yet been fully elucidated. We examined the current literature as to aetiology, treatment and possible prevention of ED following prostatectomy.
Review of the literature by a Medline search.
The most important predictors of erectile function are pre-operative erectile function and the nerve sparing nature of the procedure. The former is determined by age and vascular risk-factors whereas the latter is decided by the stage of the tumour and the skill of the surgeon. The value of intraoperative nerve mapping seems limited and the importance of nerve grafting is uncertain. Natural recovery of erection can take as long as 24 months. Patients complain about a lack of professional support. Symptomatic therapy may be applied according to the current general standards of treatment in men with ED.
尽管前列腺切除术后勃起功能障碍(ED)的高发生率已得到充分认识,但其病因和病理生理学尚未完全阐明。我们查阅了当前关于前列腺切除术后ED的病因、治疗及可能预防措施的文献。
通过医学文献数据库检索进行文献综述。
勃起功能的最重要预测因素是术前勃起功能和手术的神经保留性质。前者由年龄和血管危险因素决定,而后者由肿瘤分期和外科医生的技术决定。术中神经定位的价值似乎有限,神经移植的重要性尚不确定。勃起功能的自然恢复可能长达24个月。患者抱怨缺乏专业支持。可根据当前男性ED治疗的一般标准进行对症治疗。