异位妊娠破裂的自体输血

Autotransfusion for ruptured ectopic pregnancy.

作者信息

Selo-Ojeme D O, Onwude J L, Onwudiegwu U

机构信息

Department of Obstetrics and Gynaecology, St. John's Hospital, Wood Street, Essex, Chelmsford, UK.

出版信息

Int J Gynaecol Obstet. 2003 Feb;80(2):103-10. doi: 10.1016/s0020-7292(02)00379-x.

DOI:10.1016/s0020-7292(02)00379-x

PMID:12566181

Abstract

OBJECTIVES

Clinical outcomes following the exclusive use of autotransfusion in the management of ruptured ectopic pregnancy are reviewed.

METHODS

A MEDLINE search (1966-2002) for relevant articles documenting the exclusive use of autotransfusion, and data collection and analysis was made.

RESULTS

There were 21 studies, 16 from developing and five from developed countries, involving 632 cases of ruptured ectopic pregnancies. Hypovolemic shock with significant hemoperitoneum (>500 ml) was the most common complication. The procedure was performed completely manually in developing countries and with the help of a device in developed countries. The mean volume of autotransfused blood was over 1000 ml, with mean hemoglobin levels ranging from 6 to 12.5 g/dl. Mean posttransfusion hemoglobin levels were higher than pretransfusion levels. There was one death, thought to be due to pulmonary embolism, and nine major and minor complications.

CONCLUSIONS

Autotransfusion is useful in the management of ruptured ectopic pregnancy.

摘要

目的

回顾单纯采用自体输血治疗破裂异位妊娠后的临床结局。

方法

检索MEDLINE（1966 - 2002年）中记录单纯采用自体输血治疗的相关文章，并进行数据收集与分析。

结果

共有21项研究，其中16项来自发展中国家，5项来自发达国家，涉及632例破裂异位妊娠病例。伴有大量腹腔内出血（>500 ml）的低血容量性休克是最常见的并发症。在发展中国家该操作完全手动进行，而在发达国家借助设备完成。自体输血的平均血量超过1000 ml，平均血红蛋白水平在6至12.5 g/dl之间。输血后平均血红蛋白水平高于输血前。有1例死亡，推测死于肺栓塞，还有9例严重及轻微并发症。