破裂型异位妊娠的自体输血挽救与同种异体输血对比

Salvage autotransfusion versus homologous blood transfusion for ruptured ectopic pregnancy.

作者信息

Selo-Ojeme D O, Feyi-Waboso P A

机构信息

Department of Obstetrics and Gynecology, Barnet and Chase Farm Hospitals NHS Trust, The Ridgeway, Enfield, UK.

出版信息

Int J Gynaecol Obstet. 2007 Feb;96(2):108-11. doi: 10.1016/j.ijgo.2006.09.006. Epub 2007 Jan 19.

DOI:10.1016/j.ijgo.2006.09.006

PMID:17239882

Abstract

OBJECTIVE

To compare the clinical outcomes of simple salvage autotransfusion and homologous blood transfusion in the management of ruptured ectopic pregnancies.

METHODS

Standard statistical analysis was done and relative risk (RR) and 95% confidence interval (CI) were calculated for 112 women randomized to salvage autotransfusion or donor blood transfusion following ruptured ectopic pregnancy.

RESULTS

More women in the autologous group received more than 1000 mL of blood (RR, 6.41; 95% CI, 2.75-15.24) and had a hematocrit greater than 0.27 at discharge (RR, 3.62; 95% CI, 1.41-6.67). There were no significant differences in the incidence of postoperative fever (RR, 0.95; 95% CI, 0.43-2.01), postoperative wound infection (RR, 0.73; 95% CI, 0.17-3.19) or duration of hospital stay longer than 7 days (RR, 1.3; 95% CI, 0.44-4.31).

CONCLUSION

In resource-poor countries, women with a ruptured ectopic pregnancy receive more blood with salvage autotransfusion.

摘要

目的

比较单纯挽救性自体输血与同种异体输血在治疗破裂型异位妊娠中的临床效果。

方法

进行标准统计分析，计算112例破裂型异位妊娠后随机接受挽救性自体输血或异体输血的女性的相对危险度（RR）及95%置信区间（CI）。

结果

自体输血组更多女性接受了超过1000 mL的血液（RR，6.41；95% CI，2.75 - 15.24），且出院时血细胞比容大于0.27（RR，3.62；95% CI，1.41 - 6.67）。术后发热发生率（RR，0.95；95% CI，0.43 - 2.01）、术后伤口感染发生率（RR，0.73；95% CI，0.17 - 3.19）或住院时间超过7天的发生率（RR，1.3；95% CI，0.44 - 4.31）均无显著差异。