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无血可用时的最后手段:部署到资源有限地区的医生对术中自体输血的经验与认知

A Last Resort When There is No Blood: Experiences and Perceptions of Intraoperative Autotransfusion Among Medical Doctors Deployed to Resource-Limited Settings.

作者信息

Sjöholm Annie, Älgå Andreas, von Schreeb Johan

机构信息

Department of Global Public Health, Karolinska Institutet, 171 77, Stockholm, Sweden.

出版信息

World J Surg. 2020 Dec;44(12):4052-4059. doi: 10.1007/s00268-020-05749-y. Epub 2020 Aug 27.

Abstract

BACKGROUND

Four and a half million people die globally every year due to traumatic injuries. One major cause of preventable death is bleeding. Blood for transfusion is often unavailable in resource-limited settings, where a majority of trauma deaths occur. Intraoperative autotransfusion (IAT) has been proposed as a safe and feasible lifesaving alternative to allogeneic blood transfusion. However, there is limited knowledge regarding its use among doctors working for international non-governmental organisations (INGOs) in resource-limited settings. The aim of this study was to explore the experiences and perceptions of IAT among INGO-affiliated medical doctors with clinical experience in resource-limited settings.

METHODS

We conducted semi-structured interviews via telephone or Skype with 12 purposefully sampled surgeons and anaesthesiologists. The interviews were recorded, transcribed verbatim, and analysed using content analysis.

RESULTS

We identified three main themes relating to IAT and bottlenecks preventing the scale-up of its use: variation in techniques and systems, contextual factors, and individual medical doctor factors. The participants gave detailed reports of missed opportunities for usage of IAT in resource-limited settings. Bottlenecks included the lack of simple and cost-effective products, limited availability of protocols in the field, and insufficient knowledge and experience of IAT.

CONCLUSIONS

The participants found that simple IAT is under-utilised in resource-limited settings. Missed opportunities to use IAT were mainly associated with armed conflict settings and obstetrical emergencies. In order to meet the need for IAT in resource-limited settings, we suggest further consideration of the identified bottlenecks.

摘要

背景

全球每年有450万人死于创伤性损伤。可预防死亡的一个主要原因是出血。在大多数创伤死亡发生的资源有限地区,通常无法获得用于输血的血液。术中自体输血(IAT)已被提议作为异体输血的一种安全可行的挽救生命的替代方法。然而,在资源有限地区为国际非政府组织(INGO)工作的医生中,关于其使用的知识有限。本研究的目的是探讨在资源有限地区有临床经验的INGO附属医生对术中自体输血的经验和看法。

方法

我们通过电话或Skype对12名经过有目的抽样的外科医生和麻醉师进行了半结构化访谈。访谈进行了录音,逐字转录,并使用内容分析法进行分析。

结果

我们确定了与术中自体输血以及阻碍其扩大使用的瓶颈相关的三个主要主题:技术和系统的差异、背景因素以及个体医生因素。参与者详细报告了在资源有限地区术中自体输血使用的错失机会。瓶颈包括缺乏简单且经济高效的产品、该领域方案的可用性有限以及对术中自体输血的知识和经验不足。

结论

参与者发现,在资源有限地区,简单的术中自体输血未得到充分利用。使用术中自体输血的错失机会主要与武装冲突环境和产科紧急情况有关。为了满足资源有限地区对术中自体输血的需求,我们建议进一步考虑已确定的瓶颈。

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本文引用的文献

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Problems and Approaches for Blood Transfusion in the Developing Countries.发展中国家输血的问题与解决方法。
Hematol Oncol Clin North Am. 2016 Apr;30(2):477-95. doi: 10.1016/j.hoc.2015.11.011.
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