Fiori G P, Mazza L
Minerva Med. 1976 Mar 10;67(12):132-40.
Experimentation of two i.v. doses of a uridine-5-diphosphoglucose (UDPG) in 30 cases of acute viral hepatitis is reported. The therapeutic efficacy of the drug was assessed on qualitative and quantitative parameters indicative of liver distress. Statistically significant evidence was obtained of the efficacy of UDPG in acute and serious liver disease, and of the greater effectiveness of one of the two doses used. Excellent local and general tolerance was noted.
报告了对30例急性病毒性肝炎患者静脉注射两种剂量尿苷-5-二磷酸葡萄糖(UDPG)的实验情况。根据指示肝脏病变的定性和定量参数评估了该药物的治疗效果。获得了统计学上显著的证据,证明UDPG对急性重症肝病有效,且所使用的两种剂量之一效果更佳。观察到该药物具有良好的局部和全身耐受性。