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[抗结核化疗过程中不同肝脏保护物质的使用及其在预防和对抗代谢及功能性肝脏变化方面的有效性:临床统计学研究]

[The use of different liver-protective substances in the course of antitubercular chemotherapy and their effectiveness in preventing and countering the appearance of metabolic and functional liver changes Clinico-statistical studies].

作者信息

Natale F, Perna G

出版信息

Arch Sci Med (Torino). 1979 Oct-Dec;136(4):591-6.

PMID:550759
Abstract

An open study was run on three groups of hospitalised 40 patients with medium to serious lung TB to evaluate the effectiveness of generic liver protector drugs, UDPG, and an association of UDPG-GSH in the prevention a nd hindrance of organic and metabolic-functional liver alterations in the course of chemotherapy. It was found that UDPG--particularly in association with GSH--gave highly significant results by comparison with generic protector drugs.

摘要

对三组40例中重度肺结核住院患者进行了一项开放性研究,以评估普通肝保护药物、尿苷二磷酸葡萄糖(UDPG)以及UDPG与谷胱甘肽(GSH)联合使用在化疗过程中预防和阻止肝脏器质性及代谢功能改变的有效性。结果发现,与普通保护药物相比,UDPG——尤其是与GSH联合使用时——产生了非常显著的效果。

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