Lenzi S
Minerva Med. 1976 Sep 30;67(46):2961-74.
Toxepasi Complex (UDPG, glutathione and vitamin B12) was administered to patients with aggressive chronic hepatitis and a second group with severe cirrhosis. Changes in laboratory enzymological data indicative of the overall extent of liver damage due to cell necrosis, cholostasis and impairment of protein synthesis were evaluated. Decreases tending to normalisation were noted two weeks after the commencement of treatment, particularly in the first group. The results suggest that the complex may be usefully employed in the management of aggressive chronic hepatitis and cirrhosis of the liver.
将托克斯帕西复合物（尿苷二磷酸葡萄糖、谷胱甘肽和维生素B12）给予侵袭性慢性肝炎患者和另一组重症肝硬化患者。评估了实验室酶学数据的变化，这些数据表明由于细胞坏死、胆汁淤积和蛋白质合成受损导致的肝脏损伤的总体程度。治疗开始两周后发现有趋于正常化的下降，特别是在第一组。结果表明，该复合物可有效用于侵袭性慢性肝炎和肝硬化的治疗。
