Wang C, Liu A
Department of Neurosurgery, Institute of Neuroscience, CAMS and PUMC, Beijing 100050.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1999 Dec;21(6):415-20.
To study the various aspects of the brain-stem vascular malformations, including the histopathology, clinical presentation, neuroimaging, techniques of surgical operation.
A retrospective analysis of 100 patients with 105 brain-stem vascular malformations had underwent microsurgery from 1987 to 1997 in the institute.
Most brain-stem vascular malformations are cavernoma, some of them are not easily differentiated from telangiectasis. Meanwhile, they could also associate with venous malformation. In our group, 67% patients suffered from hemorrhage more than one time. The average number of bleeding in female is higher than in male's. There was no operative mortality. The outcome was improved and stable in 65% patients. Ninety-two patients have followed-up half a year to 11 years. Rebleeding after operation occurred in 4% cases.
Active microsurgery should be adopted carefully for the patients with symptomatic brain-stem vascular malformations, while those with asymptomatic lesions need long-term clinical observations and neuroimaging follow-up.
研究脑干血管畸形的各个方面,包括组织病理学、临床表现、神经影像学及外科手术技术。
对1987年至1997年在该研究所接受显微手术的100例患有105处脑干血管畸形的患者进行回顾性分析。
大多数脑干血管畸形为海绵状血管瘤,其中一些与毛细血管扩张症不易区分。同时,它们也可能与静脉畸形相关。在我们的研究组中,67%的患者有多次出血史。女性的平均出血次数高于男性。无手术死亡病例。65%的患者预后改善且稳定。92例患者进行了半年至11年的随访。术后再出血发生率为4%。
对于有症状的脑干血管畸形患者,应谨慎采用积极的显微手术,而对于无症状病变患者则需要长期临床观察和神经影像学随访。