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肉毒杆菌毒素治疗颞下颌关节紊乱病

Treatment of temporomandibular disorders with botulinum toxin.

作者信息

Schwartz Marvin, Freund Brian

机构信息

The Crown Institute, Toronto, Ontario, Canada.

出版信息

Clin J Pain. 2002 Nov-Dec;18(6 Suppl):S198-203. doi: 10.1097/00002508-200211001-00013.

DOI:10.1097/00002508-200211001-00013
PMID:12569969
Abstract

Temporomandibular disorder (TMD) is a collective term used to characterize a heterogeneous group of conditions involving the temporomandibular joint (TMJ) and its contiguous tissues. Although the pathologies behind TMDs have not been completely explained, the symptoms associated with these disorders are similar and are most commonly manifest as pain in the orofacial region. In preliminary studies, botulinum toxin has been used successfully to treat various pain syndromes, including TMDs. Because of the complex nature of TMDs and proximity of affected muscles to facial nerves, correct injection technique and appropriate dosing guidelines are very important for successful results. This article describes common TMDs and their treatment with botulinum toxin. Dosing guidelines and illustrations of affected muscles and target injection sites are provided.

摘要

颞下颌关节紊乱病(TMD)是一个统称,用于描述涉及颞下颌关节(TMJ)及其相邻组织的一组异质性病症。尽管TMD背后的病理机制尚未完全阐明,但与这些病症相关的症状相似,最常见的表现为口面部区域疼痛。在初步研究中,肉毒杆菌毒素已成功用于治疗包括TMD在内的各种疼痛综合征。由于TMD的复杂性以及受影响肌肉与面神经的接近程度,正确的注射技术和适当的给药指南对于取得成功的治疗效果非常重要。本文介绍了常见的TMD及其肉毒杆菌毒素治疗方法。文中提供了给药指南以及受影响肌肉和目标注射部位的图示。

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