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分娩期间胎儿心电图的ST段分析:北欧观察性多中心研究。

ST analysis of the fetal electrocardiogram during labor: Nordic observational multicenter study.

作者信息

Amer-Wåhlin I, Bördahl P, Eikeland T, Hellsten C, Norén H, Sörnes T, Rosén K G

机构信息

Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden.

出版信息

J Matern Fetal Neonatal Med. 2002 Oct;12(4):260-6. doi: 10.1080/jmf.12.4.260.266.

Abstract

OBJECTIVE

To assess the diagnostic power of cardiotocography (CTG) plus the ST interval of the electrocardiogram (ECG) clinical guidelines with combined fetal heart rate and ST waveform analysis of the fetal ECG recorded during labor, to identify an adverse labor outcome (neonatal neurological symptoms and/or metabolic acidosis).

STUDY DESIGN

An observational, multicenter study was undertaken in 12 Nordic labor wards. A total of 573 women in labor were monitored using a prototype of the STAN S 21 recorder with fetal ECG data and computerized ST analysis.

RESULTS

Fifteen cases of intrapartum fetal hypoxia identified from neurological neonatal symptoms and/or cord artery pH < 7.05 with base deficit in extracellular fluid > 12.0 mmol/l were recorded. All these cases were identified by CTG + ST clinical guidelines. Five developed neonatal symptoms and had ECG abnormalities during the first stage of labor and, of the remaining ten, eight showed ST changes during active pushing in the second stage. Another eight cases had acidemia only and normal neonatal outcome. Seven of these displayed CTG + ST abnormalities. The high sensitivity of CTG + ST to predict fetal acidosis was associated with a marked increase in positive predictive values compared with conventional CTG.

CONCLUSION

The STAN clinical guidelines identify fetuses at risk of intrapartum asphyxia.

摘要

目的

通过对产程中记录的胎儿心电图的胎心率和ST段波形进行联合分析,评估宫缩图(CTG)加上心电图(ECG)临床指南对诊断不良分娩结局(新生儿神经症状和/或代谢性酸中毒)的效能。

研究设计

在12个北欧产科病房进行了一项观察性多中心研究。使用带有胎儿心电图数据和计算机化ST分析功能的STAN S 21记录仪原型对总共573名分娩妇女进行了监测。

结果

记录了15例因新生儿神经症状和/或脐动脉pH<7.05且细胞外液碱缺失>12.0 mmol/l而确定的产时胎儿缺氧病例。所有这些病例均通过CTG + ST临床指南得以识别。5例在第一产程出现新生儿症状且伴有心电图异常,其余10例中,8例在第二产程主动用力时出现ST段改变。另外8例仅有酸血症且新生儿结局正常。其中7例显示CTG + ST异常。与传统CTG相比,CTG + ST预测胎儿酸中毒的高敏感性与阳性预测值的显著增加相关。

结论

STAN临床指南可识别产时窒息风险胎儿。

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