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Ubiquity of putative type III secretion genes among clinical and environmental Burkholderia pseudomallei isolates in Northern Australia.澳大利亚北部临床和环境类鼻疽伯克霍尔德菌分离株中假定的III型分泌基因的普遍性。
J Clin Microbiol. 2003 Feb;41(2):883-5. doi: 10.1128/JCM.41.2.883-885.2003.
2
Presence of type III secretion genes in Burkholderia pseudomallei correlates with Ara(-) phenotypes.类鼻疽伯克霍尔德菌中III型分泌基因的存在与阿拉伯糖（Ara）阴性表型相关。
J Clin Microbiol. 2000 Feb;38(2):883-5. doi: 10.1128/JCM.38.2.883-885.2000.
3
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Identification and discrimination of Burkholderia pseudomallei, B. mallei, and B. thailandensis by real-time PCR targeting type III secretion system genes.通过靶向III型分泌系统基因的实时PCR鉴定和区分伯克霍尔德菌、鼻疽伯克霍尔德菌和泰国伯克霍尔德菌
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Sensitive and specific molecular detection of Burkholderia pseudomallei, the causative agent of melioidosis, in the soil of tropical northern Australia.在澳大利亚北部热带地区土壤中对类鼻疽病病原体——伯克霍尔德菌进行灵敏且特异的分子检测。
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1
Sensitive and specific molecular detection of Burkholderia pseudomallei, the causative agent of melioidosis, in the soil of tropical northern Australia.在澳大利亚北部热带地区土壤中对类鼻疽病病原体——伯克霍尔德菌进行灵敏且特异的分子检测。
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2
Use of protein-specific monoclonal antibody-based latex agglutination for rapid diagnosis of Burkholderia pseudomallei infection in patients with community-acquired septicemia.使用基于蛋白质特异性单克隆抗体的乳胶凝集试验对社区获得性败血症患者进行类鼻疽伯克霍尔德菌感染的快速诊断。
Clin Vaccine Immunol. 2007 Jun;14(6):811-2. doi: 10.1128/CVI.00011-07. Epub 2007 Apr 11.
3
Use of a variable amplicon typing scheme reveals considerable variation in the accessory genomes of isolates of Burkholderia pseudomallei.使用可变扩增子分型方案揭示了伯克霍尔德菌假鼻疽分离株的辅助基因组存在相当大的差异。
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4
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5
Melioidosis: epidemiology, pathophysiology, and management.类鼻疽病：流行病学、病理生理学及管理
Clin Microbiol Rev. 2005 Apr;18(2):383-416. doi: 10.1128/CMR.18.2.383-416.2005.

本文引用的文献

1
Distribution of type III secretion gene clusters in Burkholderia pseudomallei, B. thailandensis and B. mallei.III型分泌基因簇在类鼻疽伯克霍尔德菌、泰国伯克霍尔德菌和鼻疽伯克霍尔德菌中的分布。
J Med Microbiol. 2002 May;51(5):374-384. doi: 10.1099/0022-1317-51-5-374.
2
A second type III secretion system in Burkholderia pseudomallei: who is the real culprit?
Microbiology (Reading). 2001 Dec;147(Pt 12):3197-9. doi: 10.1099/00221287-147-12-3197.
3
Burkholderia pseudomallei virulence: definition, stability and association with clonality.伯克霍尔德菌属假鼻疽杆菌的毒力：定义、稳定性及其与克隆性的关联
Microbes Infect. 2001 Jul;3(8):621-31. doi: 10.1016/s1286-4579(01)01417-4.
4
Burkholderia pseudomallei interferes with inducible nitric oxide synthase (iNOS) production: a possible mechanism of evading macrophage killing.嗜麦芽窄食单胞菌干扰诱导型一氧化氮合酶（iNOS）的产生：逃避巨噬细胞杀伤的一种可能机制。
Microbiol Immunol. 2001;45(4):307-13. doi: 10.1111/j.1348-0421.2001.tb02623.x.
5
Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant.通过消减杂交检测细菌毒力基因：鉴定伯克霍尔德菌假鼻疽亚种的荚膜多糖为主要毒力决定因素。
Infect Immun. 2001 Jan;69(1):34-44. doi: 10.1128/IAI.69.1.34-44.2001.
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Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature.澳大利亚北部热带地区的地方性类鼻疽病：一项为期10年的前瞻性研究及文献综述
Clin Infect Dis. 2000 Oct;31(4):981-6. doi: 10.1086/318116. Epub 2000 Oct 25.
7
Characterization and mutagenesis of fur gene from Burkholderia pseudomallei.伯克霍尔德菌属类鼻疽杆菌fur基因的特性与诱变
Gene. 2000 Aug 22;254(1-2):129-37. doi: 10.1016/s0378-1119(00)00279-1.
8
Epidemiology of arabinose assimilation in burkholderia pseudomallei isolated from patients and soil in Thailand.从泰国患者和土壤中分离出的类鼻疽伯克霍尔德菌中阿拉伯糖同化作用的流行病学研究
Southeast Asian J Trop Med Public Health. 1999 Dec;30(4):756-9.
9
Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and human-animal hosts.类鼻疽伯克霍尔德菌生态学以及环境伯克霍尔德菌属与人类-动物宿主之间的相互作用。
Acta Trop. 2000 Feb 5;74(2-3):159-68. doi: 10.1016/s0001-706x(99)00066-2.
10
The epidemiology of melioidosis in Australia and Papua New Guinea.澳大利亚和巴布亚新几内亚类鼻疽的流行病学。
Acta Trop. 2000 Feb 5;74(2-3):121-7. doi: 10.1016/s0001-706x(99)00060-1.

澳大利亚北部临床和环境类鼻疽伯克霍尔德菌分离株中假定的III型分泌基因的普遍性。

Ubiquity of putative type III secretion genes among clinical and environmental Burkholderia pseudomallei isolates in Northern Australia.

作者信息

Smith-Vaughan H C, Gal D, Lawrie P M, Winstanley C, Sriprakash K S, Currie B J

机构信息

University of Queensland, Brisbane, Australia.

出版信息

J Clin Microbiol. 2003 Feb;41(2):883-5. doi: 10.1128/JCM.41.2.883-885.2003.

DOI:10.1128/JCM.41.2.883-885.2003
PMID:12574307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC149695/
Abstract

Type III secretion (TTSI) genes of an HRP (hypersensitivity response and pathogenicity)-like locus were present in all 116 Northern Australian Burkholderia pseudomallei isolates tested but were not detected in other common environmental Burkholderia species. PCR of TTS1 genes may prove valuable as a diagnostic test [corrected].

摘要

在所有检测的116株澳大利亚北部类鼻疽伯克霍尔德菌分离株中均存在一个类过敏反应和致病性（HRP）位点的III型分泌（TTSI）基因，但在其他常见环境伯克霍尔德菌物种中未检测到。TTS1基因的PCR检测可能作为一种诊断测试具有价值[已修正]。