Effects of an odor paired with illness on startle, freezing, and analgesia in rats.

The data reported in this experiment provide the first systematic exploration of the effectiveness of an odor previously paired with an aversive reinforcer other than shock on eliciting various behavioral expressions of fear in the rat. Specifically, we measured potentiation of the acoustic startle response, freezing, and analgesia in the presence of an odor previously paired with an illness-inducing agent (lithium chloride; LiCl). We found that this odor elicited freezing and analgesia, but failed to potentiate the startle response. The results are discussed in terms of (1). potential threshold differences for various expressions of learned fear and (2). the possibility that the content of the learning established by odor-shock pairings differ from those established by odor-illness pairings.