Kim Gyung-Tae, Tsukaya Hirokazu
National Institute for Basic Biology / Center for Integrative Bioscience, 38 Nishigounaka, Myodaiji-cho, Okazaki 444-8585, Japan.
J Plant Res. 2002 Jun;115(3):169-77. doi: 10.1007/s102650200022.
Cytochrome P450 monooxygenases are a large group of heme-containing enzymes, most of which catalyze hydroxylation reactions. Since the discovery of cytochrome P450 in plants, more than 500 forms have been found, and they appear to be involved in the biosynthetic pathways of a large variety of primary and secondary metabolites. In particular, cytochrome P450s are involved in the biosynthesis of plant hormones, and play important roles in the regulation of plant growth and development. Recent genetic and functional analyses of cytochrome P450s in plants have significantly improved our understanding of not only the biosynthetic pathways themselves, but also of plant development from the perspective of hormonal control of morphogenesis. This review summarizes the present status of research on cytochrome P450s' roles in regulating the biosynthesis of plant hormones.
细胞色素P450单加氧酶是一大类含血红素的酶，其中大多数催化羟基化反应。自植物中发现细胞色素P450以来，已发现500多种形式，它们似乎参与了多种初级和次级代谢产物的生物合成途径。特别是，细胞色素P450参与植物激素的生物合成，并在植物生长发育的调控中发挥重要作用。最近对植物中细胞色素P450的遗传和功能分析，不仅显著增进了我们对生物合成途径本身的理解，也从形态发生的激素控制角度加深了对植物发育的理解。本综述总结了细胞色素P450在调节植物激素生物合成中作用的研究现状。
