Yang W, Kuang L, Deng F, Xiong J
Department of Ophthalmology, Guangzhou First Municipal People's Hospital, Guangzhou 510180, China.
Yan Ke Xue Bao. 1999 Dec;15(4):267-9.
To investigate the changes of bacterial strains in the conjunctival sac before and after intraocular surgery, as well as clinical effects of preoperative antibiotic agents.
One hundred and thirty-three eyes with intraocular surgery included 68 eyes with cataract surgery, 39 eyes with glaucoma surgery, 20 eyes with retinal detachment surgery and 6 eyes with vitretomy. Bacterial culture and pharmacologic sensitivity test were performed on the conjunctival smear from the 133 eyes with intraocular surgery before and after the operation and the anterior chamber aspirate from the 68 eyes with cataract surgery after the operation.
At the time of admission, 61 eyes(45.8%) of 133 eyes with intraocular surgery were culture-positive conjunctival smears with the following identified: Staphlococcus aureus: 23 eyes; Staphlococcus epidermidis: 25 eyes; Gram-positive rods: 13 eyes. 8 eyes(6%) had culture-positive conjunctival smears before disinfection, (Staphlococcus aureus: 3 eyes; Staphlococcus epidermidis: 5 eyes). One eye(1.5%) had culture-positive Staphylococcus epidermidis in anterior chamber aspirate of 68 eyes with cataract surgery at conclusion of surgery. Also, 4 eyes(3%) were culture-positive conjunctival smears after surgery. All the bacterial strains of the group were sensitive to Tobramycin, Gentamycin, Cephradinum(Velosel), Vancomycinum and Rifampin, but they were resistance to Tetracyclinum, Chloromycetin, Erythromycin and Ofloxacin. Eye Science 1999; 15: 267-269.
In order to prevent bacterial endophthalmitis after intraocular surgery, installation of an useful antibiotic eye drop before the surgery is important.
研究眼内手术前后结膜囊内细菌菌株的变化以及术前使用抗生素的临床效果。
133例接受眼内手术的患者，其中白内障手术68例，青光眼手术39例，视网膜脱离手术20例，玻璃体切割术6例。对133例眼内手术患者手术前后的结膜涂片以及68例白内障手术患者术后的前房穿刺液进行细菌培养和药敏试验。
入院时，133例眼内手术患者中有61例（45.8%）结膜涂片培养阳性，具体如下：金黄色葡萄球菌23例；表皮葡萄球菌25例；革兰氏阳性杆菌13例。8例（6%）在消毒前结膜涂片培养阳性（金黄色葡萄球菌3例；表皮葡萄球菌5例）。68例白内障手术患者中，1例（1.5%）术后前房穿刺液表皮葡萄球菌培养阳性。此外，4例（3%）术后结膜涂片培养阳性。该组所有菌株对妥布霉素、庆大霉素、头孢拉定（先锋霉素Ⅵ）、万古霉素和利福平敏感，但对四环素、氯霉素、红霉素和氧氟沙星耐药。《眼科》1999年；15：267 - 269。
为预防眼内手术后细菌性眼内炎，术前使用有效的抗生素滴眼液很重要。
