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[实验性暗点对多焦视网膜电图的影响]

[The influence of experimental scotoma on multifocal electroretinogram].

作者信息

Luo G, Marmor M F, Aimee C

机构信息

Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.

出版信息

Yan Ke Xue Bao. 2000 Dec;16(4):254-8.

PMID:12579783
Abstract

PURPOSE

To detect the sensitivity and the repeatability of multifocal electroretinogram (mfERG).

METHOD

The effects of experimental absolute and relative scotomas on mfERG with 103 hexagons were observed on 8 normal eyes. The scotomas were produced by simultaneous and multi located masks on the hexagons of the screen in 6 different locations with black paper, and the neutral filters of 0.3 and 0.6 log unit. The repeatability was evaluated by analysis the data from 5 unmasked hexagons in 4 successive tests.

RESULTS

When the hexagons were 1/2 or wholly masked with the black paper and the two kinds of the filters, the amplitudes of N1 and P1 waves in these areas were significantly decreased as with the reduced transferability of light. When the hexagon was 1/3 masked, there were no significant differences between the different kinds of mask and the unmasked control. There were no significant changes in the datas from the selected unmasked hexagons in the 4 successive recordings.

CONCLUSION

mfERG is an unique sensitive visual electrophysiological test with high sensitivity and good repeatability. When 103 hexagons stimulating pattern is used, it could detect the scotoma larger than 1/3 of each hexagon.

摘要

目的

检测多焦视网膜电图(mfERG)的敏感性和可重复性。

方法

在8只正常眼睛上观察实验性绝对和相对暗点对具有103个六边形的mfERG的影响。暗点通过用黑纸在屏幕六边形的6个不同位置同时进行多处遮挡以及使用0.3和0.6对数单位的中性滤光片产生。通过分析连续4次测试中5个未遮挡六边形的数据来评估可重复性。

结果

当六边形被黑纸和两种滤光片1/2或全部遮挡时,这些区域中N1和P1波的振幅随着光传递性降低而显著降低。当六边形被1/3遮挡时,不同类型的遮挡与未遮挡对照之间无显著差异。在连续4次记录中,所选未遮挡六边形的数据无显著变化。

结论

mfERG是一种独特的敏感视觉电生理检查,具有高敏感性和良好的可重复性。当使用103个六边形刺激模式时,它能够检测到大于每个六边形1/3的暗点。

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