[蛋白质和肽类药物聚乙二醇化中的问题与解决方案] - Suppr

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超能文献

[Problems and solutions in pegylation of protein and peptide drugs].

作者信息

Jiang Zhong-yi, Gao Rong, Wang Yan-qiang, Sun Yan

机构信息

School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.

出版信息

Yao Xue Xue Bao. 2002 May;37(5):396-400.

PMID:12579849

Abstract

摘要

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相似文献

[Problems and solutions in pegylation of protein and peptide drugs].

Yao Xue Xue Bao. 2002 May;37(5):396-400.

PEGylation, successful approach to drug delivery.

Drug Discov Today. 2005 Nov 1;10(21):1451-8. doi: 10.1016/S1359-6446(05)03575-0.

Conjugates of peptides and proteins to polyethylene glycols.

Methods Mol Biol. 2004;283:45-70. doi: 10.1385/1-59259-813-7:045.

A new approach to bioconjugates for proteins and peptides ("pegylation") utilising living radical polymerisation.

Chem Commun (Camb). 2004 Sep 21(18):2026-7. doi: 10.1039/b407712a. Epub 2004 Jul 28.

PEGylation of native disulfide bonds in proteins.

Nat Protoc. 2006;1(5):2241-52. doi: 10.1038/nprot.2006.346.

Emerging PEGylated drugs.

Expert Opin Emerg Drugs. 2009 Jun;14(2):363-80. doi: 10.1517/14728210902907847.

Effect of pegylation on pharmaceuticals.

Nat Rev Drug Discov. 2003 Mar;2(3):214-21. doi: 10.1038/nrd1033.

Peptide and protein PEGylation: a review of problems and solutions.

Biomaterials. 2001 Mar;22(5):405-17. doi: 10.1016/s0142-9612(00)00193-9.

Site-specific PEGylation of proteins: recent developments.

J Org Chem. 2014 Nov 21;79(22):10727-33. doi: 10.1021/jo502136n. Epub 2014 Nov 3.

Characterization of poly(ethylene glycol) and PEGylated products by LC/MS with postcolumn addition of amines.

Anal Chem. 2009 Jan 15;81(2):567-77. doi: 10.1021/ac801711u.

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