Qiu G, Hu Z, Li M, Liu S
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Yan Ke Xue Bao. 1998 Sep;14(3):182-6.
To discuss the fluorescein angiographic features and diagnosis as well as differential diagnosis.
In our hospital, we have found three cases of UAIM, one of them has eccentric maculopathy, another has papillitis, and the third associates with pregnancy. Each has characteristic clinical findings. We have made the diagnosis base on ophthalmoscopy and fluorescein angiography (FA).
Three patients with UAIM have been experienced sudden unilateral decreased visual acuity. The significant changes on fundus are retinal pigment epithelium (RPE) thickening with neurosensory retinal detachment with in the macular area. FA showed early patchy hypofluorescence and hyperfluorescence at the level of the RPE. 'Bull's eye appearance may occur in the macular area after the acute stage of the disease. The clinical findings are similar to what the foreign report described. But there were no previous reports in China.
We can establish the diagnosis on the base of clinical and fundus features associated with fluorescein angiographic findings. However, the etiology and pathology could not be identified. It required further research.
探讨非典型急性黄斑视网膜病变(UAIM)的荧光素血管造影特征、诊断及鉴别诊断。
我院发现3例UAIM患者,其中1例有黄斑病变,另1例有视乳头炎,第3例与妊娠相关。每例均有特征性临床表现。我们根据检眼镜检查和荧光素血管造影(FA)做出诊断。
3例UAIM患者均突然出现单眼视力下降。眼底的显著变化是黄斑区视网膜色素上皮(RPE)增厚伴神经感觉层视网膜脱离。FA显示RPE层面早期有散在的低荧光和高荧光。疾病急性期过后,黄斑区可能出现“靶心样外观”。临床所见与国外报道相似。但国内此前尚无相关报道。
我们可根据临床、眼底特征及荧光素血管造影结果做出诊断。然而,病因和病理尚不明确,有待进一步研究。