• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

HHV-6 DNAaemia in patients with multiple sclerosis in Kuwait.

作者信息

Al-Shammari S, Nelson R F, Voevodin A

机构信息

Division of Neurology, Faculty of Medicine, University of Kuwait, Safat, Kuwait.

出版信息

Acta Neurol Scand. 2003 Feb;107(2):122-4. doi: 10.1034/j.1600-0404.2003.01234.x.

DOI:10.1034/j.1600-0404.2003.01234.x
PMID:12580862
Abstract

OBJECTIVE

To study the presence of active human herpesvirus type-6 (HHV-6) infection indicated by the presence of HHV-6 DNA in serum (DNAaemia) in patients suffering from multiple sclerosis (MS) in Kuwait.

MATERIAL AND METHODS

Sera from 24 patients with MS (18 relapsing-remitting, six secondary progressive disease), control sera from 13 patients suffering from other neurological diseases and sera from 20 healthy volunteers were examined for the presence of HHV-6 DNA by nested polymerase chain reaction (PCR) test.

RESULTS

None of the MS patients, nor patient controls were positive for HHV-6 DNAaemia while, one of the normal healthy controls was positive for HHV-6 DNAaemia.

CONCLUSION

HHV-6 DNAaemia, indicating active HHV-6 infection could not be demonstrated in a sample of Kuwaiti patients suffering from active clinically definite MS. There is no evidence to incriminate this virus in the pathogenesis of MS in Kuwait.

摘要

相似文献

1
HHV-6 DNAaemia in patients with multiple sclerosis in Kuwait.
Acta Neurol Scand. 2003 Feb;107(2):122-4. doi: 10.1034/j.1600-0404.2003.01234.x.
2
Human herpesvirus-6 and multiple sclerosis: relapsing-remitting versus secondary progressive.人类疱疹病毒6型与多发性硬化症:复发缓解型与继发进展型
Mult Scler. 2007 Jun;13(5):578-83. doi: 10.1177/1352458506072667. Epub 2007 Feb 16.
3
Leukotropic herpesviruses in multiple sclerosis.多发性硬化症中的亲白细胞性疱疹病毒
Mult Scler. 2000 Apr;6(2):66-8. doi: 10.1177/135245850000600202.
4
Human herpesvirus 6 and effectiveness of interferon β1b in multiple sclerosis patients.人类疱疹病毒 6 与多发性硬化症患者干扰素 β1b 的疗效。
Eur J Neurol. 2011 Aug;18(8):1027-35. doi: 10.1111/j.1468-1331.2011.03410.x. Epub 2011 Apr 25.
5
Identification of human herpesviruses 1 to 8 in Tunisian multiple sclerosis patients and healthy blood donors.鉴定突尼斯多发性硬化症患者和健康献血者中的人类疱疹病毒 1 至 8 型。
J Neurovirol. 2012 Feb;18(1):12-9. doi: 10.1007/s13365-011-0056-z. Epub 2011 Nov 5.
6
Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis.抗 HHV-6 IgG 效价显著预测多发性硬化症的后续复发风险。
Mult Scler. 2012 Jun;18(6):799-806. doi: 10.1177/1352458511428081. Epub 2011 Nov 14.
7
Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6.人类疱疹病毒(HHV)7感染与HHV - 6感染相关的特征及获得情况
J Infect Dis. 2006 Apr 15;193(8):1063-9. doi: 10.1086/503434. Epub 2006 Mar 6.
8
Clinical parameters and HHV-6 active replication in relapsing-remitting multiple sclerosis patients.复发缓解型多发性硬化症患者的临床参数与人类疱疹病毒6型的活跃复制
J Clin Virol. 2006 Dec;37 Suppl 1:S24-6. doi: 10.1016/S1386-6532(06)70007-5.
9
The participation of varicella zoster virus in relapses of multiple sclerosis.水痘带状疱疹病毒在多发性硬化症复发中的作用。
Clin Neurol Neurosurg. 2014 Apr;119:44-8. doi: 10.1016/j.clineuro.2013.12.020. Epub 2014 Jan 10.
10
Human herpesvirus-6 viral load and antibody titer in serum samples of patients with multiple sclerosis.人类疱疹病毒 6 病毒载量和血清样本中多发性硬化症患者的抗体滴度。
J Microbiol Immunol Infect. 2011 Aug;44(4):247-51. doi: 10.1016/j.jmii.2010.08.002. Epub 2011 Jan 20.

引用本文的文献

1
The Probable Infectious Origin of Multiple Sclerosis.多发性硬化症可能的感染起源
NeuroSci. 2023 Sep 7;4(3):211-234. doi: 10.3390/neurosci4030019. eCollection 2023 Sep.
2
Association of infections with multiple sclerosis in Gulf Cooperation Council countries: a review.海湾合作委员会国家感染与多发性硬化症的关联:综述
J Int Med Res. 2020 Apr;48(4):300060519884151. doi: 10.1177/0300060519884151. Epub 2019 Dec 27.
3
Viruses and multiple sclerosis.病毒与多发性硬化。
CNS Neurol Disord Drug Targets. 2012 Aug;11(5):528-44. doi: 10.2174/187152712801661220.
4
Human herpesvirus 6 infection as a trigger of multiple sclerosis.人类疱疹病毒 6 感染作为多发性硬化症的触发因素。
Mayo Clin Proc. 2010 Nov;85(11):1023-30. doi: 10.4065/mcp.2010.0350. Epub 2010 Oct 6.
5
Early and late HHV-6 gene transcripts in multiple sclerosis lesions and normal appearing white matter.多发性硬化症病灶及正常外观白质中HHV - 6基因的早期和晚期转录本
Brain. 2005 Mar;128(Pt 3):516-27. doi: 10.1093/brain/awh390. Epub 2005 Jan 19.
6
Update on human herpesvirus 6 biology, clinical features, and therapy.人疱疹病毒6型生物学、临床特征及治疗进展
Clin Microbiol Rev. 2005 Jan;18(1):217-45. doi: 10.1128/CMR.18.1.217-245.2005.