Jain Rina, Basinski Antoni, Kreder Hans J
San Diego Sports Medicine and Orthopaedic Center, 6719 Alvarado Road, Suite 200, 92120 San Diego, CA, USA.
Int Orthop. 2003;27(1):11-7. doi: 10.1007/s00264-002-0404-y. Epub 2002 Nov 12.
We retrospectively reviewed a population database and a case series to compare the mortality of operative and nonoperative treatment of hip fractures in patients with severe comorbidity. Nonoperative treatment of hip fractures (bed rest or early weight bearing) was administered based on medical assessment of perioperative risk. Comparison of 30-day mortality was performed between the nonoperatively and operatively treated groups. We found that of 50,235 of hip fractures that occurred between 1992 and 1998, 89.4% were treated operatively. Thirty-day mortality rate in the nonoperatively treated patients (18.8%) was higher than the rate in operatively treated patients (11.0%) (odds ratio 1.7 times, 95% confidence interval (CI) 1.6, 1.8). In the case series, of 62 elderly patients with severe comorbidity treated nonoperatively, 41 had bed rest/traction, while 21 were mobilized early. A group of operatively treated patients (n=108) was compared to nonoperatively treated patients. Mortality with nonoperative treatment was higher with bed rest (73%) compared to early mobilization (odds ratio 3.8, 95% CI 1.1-14.0). There was no significant difference in mortality between operatively treated patients (29%) and patients treated nonoperatively with immediate mobilization (19%). Bed rest was 2.5 times more likely to be associated with mortality compared to operative treatment (95% CI 1.1-5.5).
我们回顾性分析了一个人群数据库和一组病例,以比较严重合并症患者髋部骨折手术治疗与非手术治疗的死亡率。根据围手术期风险的医学评估对髋部骨折进行非手术治疗(卧床休息或早期负重)。对非手术治疗组和手术治疗组的30天死亡率进行比较。我们发现,在1992年至1998年间发生的50235例髋部骨折中,89.4%接受了手术治疗。非手术治疗患者的30天死亡率(18.8%)高于手术治疗患者(11.0%)(比值比1.7倍,95%置信区间(CI)1.6,1.8)。在该病例系列中,62例非手术治疗的老年严重合并症患者中,41例卧床休息/牵引,21例早期活动。将一组手术治疗患者(n = 108)与非手术治疗患者进行比较。与早期活动相比,卧床休息的非手术治疗死亡率更高(73%)(比值比3.8,95%CI 1.1 - 14.0)。手术治疗患者(29%)和立即活动的非手术治疗患者(19%)的死亡率无显著差异。与手术治疗相比,卧床休息与死亡相关的可能性高2.5倍(95%CI 1.1 - 5.5)。