Lerinck P, Jortay A, Gilliavod S, Heimann R
Acta Chir Belg. 1976 Mar;75(2):200-11.
144 patients with a carcinoma of the upper airways and digestive tract were examined at necropsy in the Institut Bordet, between January 1, 1960 and December 31, 1973. The study shows that 43% of these patients had distant metastases and that among these 2/3 were in local recurrence. Only 1/4 of the metastases had been recognized before death: most of them appearing in the first year following the diagnosis of the primary tumor. Survival of patients with metastases is short, most of them dying within 3 months after metastatic discovery. There seems to be no evident relationship between the initial degree of extension of the tumor and the risk of later metastatic dissemination. In the search for the most frequent metastases, located in the lungs, liver and skeleton, one should use pulmonary laminography and liver tests combined to scanning and laparoscopy.
1960年1月1日至1973年12月31日期间,在博尔德研究所对144例上呼吸道和消化道癌患者进行了尸检。研究表明,这些患者中有43%发生了远处转移,其中2/3同时伴有局部复发。只有1/4的转移灶在死前被发现:大多数转移灶在原发性肿瘤诊断后的第一年内出现。发生转移的患者生存期较短,大多数在发现转移后3个月内死亡。肿瘤最初的扩展程度与后期发生转移播散的风险之间似乎没有明显关系。在寻找最常见的转移部位(肺、肝和骨骼)时,应联合使用肺部体层摄影术、肝脏检查以及扫描和腹腔镜检查。