Return of the chalones.
作者信息
Gamer Laura W, Nove John, Rosen Vicki
机构信息
Department of Oral and Developmental Biology, Harvard School of Dental Medicine and The Forsyth Institute, Boston, MA 02115, USA.
出版信息
Dev Cell. 2003 Feb;4(2):143-4. doi: 10.1016/s1534-5807(03)00027-3.
Abstract
Members of the TGFbeta superfamily play many roles in embryonic development and adult tissue homeostasis. Now recent work focused on growth and differentiation factors (GDFs) suggest that these TGFbeta-like molecules may also control organ size and may, in fact, be the long sought after chalones, or negative growth regulators.
摘要
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