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同期颈动脉内膜切除术与心脏手术——额外的危险因素还是安全措施?

Simultaneous carotid endarterectomy and cardiac surgery--additional risk factor or safety procedure?

作者信息

Gansera B, Angelis I, Weingartner J, Neumaier-Prauser P, Spiliopoulos K, Kemkes B M

机构信息

Department of Cardiovascular Surgery, Klinikum Bogenhausen, Munich, Germany.

出版信息

Thorac Cardiovasc Surg. 2003 Feb;51(1):22-7. doi: 10.1055/s-2003-37282.

Abstract

BACKGROUND

The occurrence of severe carotid artery disease in more than 12 % of patients requiring CABG results in a discrepancy concerning the best treatment for both diseases. We reviewed the early outcome of patients with CABG and/or valve replacement and simultaneous carotid endarterectomy (CEA).

METHODS

We evaluated retrospectively 244 patients operated simultaneously between 7/94 and 10/2001. 209 patients received CABG; 35 patients CABG and/or valve replacement. Mean age was 68 years. 188 patients were male. We analyzed risk factors, morbidity, incidence of neurological complications and 30 day mortality.

RESULTS

Perioperative stroke with hemiplegia occurred in 3.3 % (8 patients). 4 of these patients showed contralateral carotid artery occlusion, 2 contralateral severe stenosis. 2 patients (0.8 %) experienced prolonged reversible ischemic neurological deficit (PRIND), 4 patients (1.6 %) transient ischemic attack (TIA). 30-day lethality was 4.5 %. 3 patients died due to low cardiac output, 6 patients due to extracardial reasons, 2 patients (0.8 %) developed a cerebral death.

CONCLUSIONS

Simultaneous CEA and cardiac surgery can be performed with an acceptable risk for neurological complications and mortality. Occlusion of contralateral carotid artery could be identified as an evident predictor for increased neurological complications. Compared to two-stage procedures, combined operations yield a reduction of hospital costs.

摘要

背景

在需要进行冠状动脉旁路移植术(CABG)的患者中,超过12%患有严重的颈动脉疾病,这使得对于两种疾病的最佳治疗方法存在差异。我们回顾了接受CABG和/或瓣膜置换术以及同期颈动脉内膜切除术(CEA)患者的早期结果。

方法

我们回顾性评估了1994年7月至2001年10月期间同时接受手术的244例患者。209例患者接受了CABG;35例患者接受了CABG和/或瓣膜置换术。平均年龄为68岁。188例患者为男性。我们分析了危险因素、发病率、神经并发症发生率和30天死亡率。

结果

围手术期发生偏瘫性卒中的患者占3.3%(8例)。其中4例患者对侧颈动脉闭塞,2例对侧严重狭窄。2例患者(0.8%)出现了长时间可逆性缺血性神经功能缺损(PRIND),4例患者(1.6%)出现短暂性脑缺血发作(TIA)。30天死亡率为4.5%。3例患者死于低心排血量,6例患者死于心外原因,2例患者(0.8%)发生脑死亡。

结论

同期进行CEA和心脏手术,神经并发症和死亡率风险可接受。对侧颈动脉闭塞可被确定为神经并发症增加的明显预测因素。与分期手术相比,联合手术可降低住院费用。

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