Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Angiology. 2010 Oct;61(7):705-10. doi: 10.1177/0003319710369792. Epub 2010 May 24.
Neurological complications and mortality within 30 days following carotid endarterectomy (CEA) alone or with concomitant cardiac surgery/cardiopulmonary bypass (CPB) were assessed in patients with or without contralateral occlusion of the internal carotid artery (CO-ICA).Of 335 patients undergoing CEA, 173 underwent concomitant cardiac surgery with CPB. Group A consisted of 260 patients without CO-ICA and group B of 75 patients with CO-ICA. The neurological complications (peripheral nerve damage, transient ischemic attack [TIA], prolonged reversible ischemic neurological deficit [PRIND], and stroke) and the Rankin index within 24 hours and 30 days postoperatively were compared. Strokes within 24 hours were significantly increased (P = .006) in group B (11%) compared with A (3.1%); TIA and PRIND did not differ (P = .33). The overall neurological complications and in particular for peripheral neurological damage, TIA/PRIND, and stroke did not differ within the 30-day-period postsurgery. A significantly higher stroke rate within 24 hours postsurgery occurred in patients with CO-ICA.
评估了颈动脉内膜切除术 (CEA) 单独或合并心脏手术/体外循环 (CPB) 后 30 天内伴有或不伴有对侧颈内动脉闭塞 (CO-ICA) 的患者的神经并发症和死亡率。在 335 例接受 CEA 的患者中,有 173 例合并 CPB 进行心脏手术。A 组包括 260 例无 CO-ICA 的患者和 B 组 75 例有 CO-ICA 的患者。比较了术后 24 小时和 30 天内的神经并发症(周围神经损伤、短暂性脑缺血发作 [TIA]、可逆性缺血性神经功能缺损延长 [PRIND] 和中风)和 Rankin 指数。B 组(11%)术后 24 小时内中风发生率明显高于 A 组(3.1%)(P =.006);TIA 和 PRIND 无差异(P =.33)。术后 30 天内,整体神经并发症,特别是周围神经损伤、TIA/PRIND 和中风,在两组间无差异。术后 24 小时内,CO-ICA 患者的中风发生率明显更高。