Gansera Brigitte, Schmidtler Fabian, Weingartner Josef, Kiask Theodor, Gundling Felix, Hapfelmeier Alexander, Eichinger Walter
Department of Cardiovascular Surgery, Clinic Bogenhausen, Munich, Germany.
Thorac Cardiovasc Surg. 2012 Dec;60(8):508-16. doi: 10.1055/s-0032-1311533. Epub 2012 Jul 12.
The occurrence of severe carotid artery disease in more than 12% of patients requiring coronary artery bypass grafting (CABG) results in a discrepancy concerning best treatment for both diseases. We reviewed the early outcome of patients with CABG and/or valve replacement (VR) and simultaneous carotid endarterectomy (CEA).
We retrospectively evaluated 386 patients after simultaneous operation between 7/1994 and 9/2010. Total 326 patients received isolated CABG, 56 CABG and/ or VR, 4 aortic surgery. Mean age was 68.3 years (range: 45 to 87). Male patients were 229. Severity of stenosis at operated side was 70 to 80% in 167, 80 to 99% in 219 patients. Total 164 patients showed bilateral carotid stenosis, 32 had contralateral occlusion. We analyzed risk factors, morbidity, incidence of neurological events, and 30-day mortality.
Perioperative stroke with hemiplegia occurred in 10 patients (2.6%). Three patients experienced PRIND, seven TIA. A 30-day mortality was 5.2%. Total 8 deaths were cardiac related, 10 due to extracardial reasons, and 2 patients developed a cerebral death.
Simultaneous CEA and cardiac surgery can be performed with a low risk for neurological complications and acceptable mortality. Occlusion of contralateral carotid artery could be identified as an evident predictor for increased neurological complications.
在需要冠状动脉搭桥术(CABG)的患者中,超过12%发生严重颈动脉疾病,这导致了对于这两种疾病的最佳治疗存在差异。我们回顾了接受冠状动脉搭桥术和/或瓣膜置换术(VR)并同时行颈动脉内膜切除术(CEA)患者的早期结局。
我们回顾性评估了1994年7月至2010年9月间同时进行手术的386例患者。其中326例患者接受单纯冠状动脉搭桥术,56例接受冠状动脉搭桥术和/或瓣膜置换术,4例接受主动脉手术。平均年龄为68.3岁(范围:45至87岁)。男性患者229例。手术侧狭窄严重程度为70%至80%的有167例,80%至99%的有219例。共有164例患者表现为双侧颈动脉狭窄,32例对侧闭塞。我们分析了危险因素、发病率、神经事件发生率和30天死亡率。
围手术期发生偏瘫性卒中的有10例(2.6%)。3例发生术后认知功能障碍(PRIND),7例发生短暂性脑缺血发作(TIA)。30天死亡率为5.2%。死亡的8例与心脏相关,10例为心外原因,2例发生脑死亡。
同时进行颈动脉内膜切除术和心脏手术,神经并发症风险低,死亡率可接受。对侧颈动脉闭塞可被确定为神经并发症增加的明显预测因素。