André Malin, Odenholt Inga, Schwan Ake, Axelsson Inge, Eriksson Margareta, Hoffman Mikael, Mölstad Sigvard, Runehagen Arne, Lundborg Cecilia Stålsby, Wahlström Rolf
Center for Clinical Research, Falun, Sweden.
Scand J Infect Dis. 2002;34(12):880-6. doi: 10.1080/0036554021000026952.
A diagnosis/antibiotic prescribing study was performed in 5 counties in Sweden for 1 week in November 2000. As part of this study, the characteristics and clinical management of patients with upper respiratory tract infections (n = 2899) in primary care were analyzed. Almost half of the patients were aged < 15 y and one-fifth of the patients consulted out of hours. Of all patients seeking primary care for upper respiratory tract infections, 56.0% were prescribed an antibiotic. Almost all patients who were given the diagnoses streptococcal tonsillitis, acute otitis media or acute sinusitis were prescribed antibiotics, compared to 10% of patients with common cold or acute pharyngitis. The most frequently prescribed antibiotic was penicillin V (79.2%) and this was even more pronounced out of hours, when the diagnoses otitis media and streptococcal tonsillitis were more frequently used. In patients with common cold and acute pharyngitis, the percentage who received antibiotics increased with increasing length of symptoms and increasing CRP levels. In patients with acute pharyngitis or streptococcal tonsillitis, antibiotics were prescribed less frequently provided streptococcal tests were performed. The management of patients with upper respiratory tract infections in general practice seems to be in good agreement with current Swedish guidelines. However, the study indicates some areas for improvement. The diagnosis of acute sinusitis seems to have been overestimated and used only to justify antibiotic treatment.
2000年11月,在瑞典的5个县进行了一项为期1周的诊断/抗生素处方研究。作为该研究的一部分,对初级保健中患有上呼吸道感染的患者(n = 2899)的特征和临床管理进行了分析。几乎一半的患者年龄小于15岁,五分之一的患者在非工作时间就诊。在所有因上呼吸道感染寻求初级保健的患者中,56.0%的患者被开具了抗生素。几乎所有被诊断为链球菌性扁桃体炎急性中耳炎或急性鼻窦炎的患者都被开具了抗生素,相比之下,普通感冒或急性咽炎患者中这一比例为10%。最常开具的抗生素是青霉素V(79.2%),在非工作时间更为明显,此时中耳炎和链球菌性扁桃体炎的诊断更为频繁。在普通感冒和急性咽炎患者中,接受抗生素治疗的百分比随着症状持续时间的延长和CRP水平的升高而增加。在急性咽炎或链球菌性扁桃体炎患者中,如果进行了链球菌检测,开具抗生素的频率会降低。全科医疗中上呼吸道感染患者的管理似乎与当前瑞典指南高度一致。然而,该研究指出了一些有待改进的方面。急性鼻窦炎的诊断似乎被高估了,仅被用作抗生素治疗的理由。