Biała Martyna, Leśnik Patrycja, Babicki Mateusz, Knysz Brygida
Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiences, Wroclaw Medical University, 51-149 Wroclaw, Poland.
Department of Microbiology, Wroclaw Medical University, 50-368 Wroclaw, Poland.
J Clin Med. 2025 Mar 16;14(6):2008. doi: 10.3390/jcm14062008.
Acute pharyngitis is one of the most prevalent disorders seen in general practitioners' consultations. Most cases of acute pharyngitis in adults are caused by respiratory viruses and are self-limited. However, clinical manifestations of viral pharyngitis can overlap with bacterial pharyngitis, mainly caused by group A (GAS). A rapid antigen test for GAS can help diagnose streptococcal pharyngitis, but misdiagnosing infection in a patient with a viral condition can lead to inappropriate antibiotic use. Some patients with a sore throat due to a virus or other causes will test positive for GAS because of carriage. The aim of our study was to analyze rapid strep test results in healthy adults. A cohort study was conducted in an outpatient clinic in Wroclaw. We used the rapid strep test . A total of 350 healthy volunteers (≥18 years old) were enrolled in this study. The presence of , based on a rapid strep test, was detected in 17 adults (4.9%). The strep test positivity rate was higher in younger adults. In healthy individuals in Poland, the prevalence of pharyngeal carriage of GAS is 4.9%. This finding emphasizes that the rapid antigen detection test should only be used in cases of suspected bacterial pharyngitis to avoid inappropriate antibiotic use.
急性咽炎是全科医生门诊中最常见的疾病之一。大多数成人急性咽炎病例由呼吸道病毒引起,具有自限性。然而,病毒性咽炎的临床表现可能与主要由A组链球菌(GAS)引起的细菌性咽炎重叠。GAS快速抗原检测有助于诊断链球菌性咽炎,但将病毒感染患者误诊可能导致不恰当使用抗生素。一些因病毒或其他原因导致喉咙痛的患者由于携带GAS会检测呈阳性。我们研究的目的是分析健康成年人的快速链球菌检测结果。在弗罗茨瓦夫的一家门诊诊所进行了一项队列研究。我们使用了快速链球菌检测。共有350名健康志愿者(≥18岁)参与了本研究。基于快速链球菌检测,17名成年人(4.9%)检测到GAS。年轻人的链球菌检测阳性率更高。在波兰的健康个体中,GAS咽部携带率为4.9%。这一发现强调,快速抗原检测仅应在疑似细菌性咽炎的病例中使用,以避免不恰当使用抗生素。