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基于快速抗原检测试验的波兰健康成年人无症状A组携带率

Prevalence of Asymptomatic Group A Carriage Based on Rapid Antigen Detection Test in Healthy Adults in Poland.

作者信息

Biała Martyna, Leśnik Patrycja, Babicki Mateusz, Knysz Brygida

机构信息

Department of Infectious Diseases, Liver Diseases and Acquired Immune Deficiences, Wroclaw Medical University, 51-149 Wroclaw, Poland.

Department of Microbiology, Wroclaw Medical University, 50-368 Wroclaw, Poland.

出版信息

J Clin Med. 2025 Mar 16;14(6):2008. doi: 10.3390/jcm14062008.

Abstract

Acute pharyngitis is one of the most prevalent disorders seen in general practitioners' consultations. Most cases of acute pharyngitis in adults are caused by respiratory viruses and are self-limited. However, clinical manifestations of viral pharyngitis can overlap with bacterial pharyngitis, mainly caused by group A (GAS). A rapid antigen test for GAS can help diagnose streptococcal pharyngitis, but misdiagnosing infection in a patient with a viral condition can lead to inappropriate antibiotic use. Some patients with a sore throat due to a virus or other causes will test positive for GAS because of carriage. The aim of our study was to analyze rapid strep test results in healthy adults. A cohort study was conducted in an outpatient clinic in Wroclaw. We used the rapid strep test . A total of 350 healthy volunteers (≥18 years old) were enrolled in this study. The presence of , based on a rapid strep test, was detected in 17 adults (4.9%). The strep test positivity rate was higher in younger adults. In healthy individuals in Poland, the prevalence of pharyngeal carriage of GAS is 4.9%. This finding emphasizes that the rapid antigen detection test should only be used in cases of suspected bacterial pharyngitis to avoid inappropriate antibiotic use.

摘要

急性咽炎是全科医生门诊中最常见的疾病之一。大多数成人急性咽炎病例由呼吸道病毒引起,具有自限性。然而,病毒性咽炎的临床表现可能与主要由A组链球菌(GAS)引起的细菌性咽炎重叠。GAS快速抗原检测有助于诊断链球菌性咽炎,但将病毒感染患者误诊可能导致不恰当使用抗生素。一些因病毒或其他原因导致喉咙痛的患者由于携带GAS会检测呈阳性。我们研究的目的是分析健康成年人的快速链球菌检测结果。在弗罗茨瓦夫的一家门诊诊所进行了一项队列研究。我们使用了快速链球菌检测。共有350名健康志愿者(≥18岁)参与了本研究。基于快速链球菌检测,17名成年人(4.9%)检测到GAS。年轻人的链球菌检测阳性率更高。在波兰的健康个体中,GAS咽部携带率为4.9%。这一发现强调,快速抗原检测仅应在疑似细菌性咽炎的病例中使用,以避免不恰当使用抗生素。

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