镉和锌处理大鼠肝脏中的核锌
Nuclear zinc in liver of cadmium and zinc treated rats.
作者信息
Bataineh Ziad M, Al-Alami Jamil R
机构信息
Department of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
出版信息
Indian J Exp Biol. 2002 Sep;40(9):1001-4.
X-ray microanalysis was performed to detect quantitatively, the variation of the nuclear zinc in the liver cells of rats. The nuclear zinc concentration showed statistical decrease and increase in response to cadmium and zinc treatments, respectively. The results suggest that the liver responds differently to cadmium and zinc treatments. The difference in response to either treatment may reflect different mechanisms of zinc transport and metabolism in the liver. The difference in binding affinity of metallothionein (MT) may suggest the involvement of Mt in the metabolism and transport of zinc, an effect, which may be modified by treatment.
进行了X射线微量分析，以定量检测大鼠肝细胞中核锌的变化。核锌浓度分别显示出对镉和锌处理的统计学下降和增加。结果表明，肝脏对镉和锌处理的反应不同。对任何一种处理的反应差异可能反映了肝脏中锌转运和代谢的不同机制。金属硫蛋白（MT）结合亲和力的差异可能表明MT参与了锌的代谢和转运，这种作用可能会因处理而改变。
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